혈액배양에서 분리된 Extended Spectrum β-Lactamase 생성균의 역학적 특성 조사 = Evaluation of Epidemic Characterstics of Extended Spectrum β-Lactamase Producing Bacteria Isolated from Blood Cultures

다국어 초록 (Multilingual Abstract)

the data which analyze the results of blood cultures are crucial basic information of the empirical therapy for patients with infection since the patterns of the species of microorganism isolated from blood and the results of antibiotics resistance of in-patients as well as out-patients in one hospital in the middle area of South Korea from 2004 to 2006. Blood culture was performed with BacT/Alert 3D(North Carolina, Durham, USA) for 5 days using BacT/Alert SA (Areobic) and BacT/Alert SN (Aneorbic) medium for adult patient and BacT/Alert PF medium for children patients. The antibiotic susceptibility test was performed with VITEK (BioMerieux vitek. Hazelwood. Missori. USA) automated identification as well as susceptibility equipments. Total 39,305 cases of blood culture sample were investigated and positive patients of 2,216 (20.0%) were found. Among those, there were 40 patient with ESBL positive, and blood culture positive smples were 4,798 (12.2%). ESBL positive bacteria were found in 86 samples (including double checked culture bacteria). The majority of ESBL producing bacteria were E. coli, K. pneumoniae and K. oxitoca as ordering based on the number. The research showed the results that there were monre females than male with the bacterias, more E. coli in over 50 years old aged group than other bacterias and largest number of patients with 13 patient (32.5%) in Chungcheongnam – do province were found. he most common ESBL producing bacteria were E. coli throughout 3 years, but K. pneumoniae and K. ocitoca were also fairly found. Interestingly, E. coli was highly found in over 50 years old patients. In conclusion, recovery progress of patients will be badly affected by the high emergence rate of ESBL producing bacteria due to the using of broad spectrum antibiotics. Therefore, significant considering is necessary in the antibiotic use, and continuous infection control and trace observations for all lpatients in hospitals including infected patients are required.

목차 (Table of Contents)

• Ⅰ. 서론
• Ⅲ. 대상 및 연구방법
• Ⅲ. 결과
• Ⅳ. 고찰 및 결과