프락셔날 이산화탄소레이저의 원리와 적용 = Principles and Practices of Fractional Carbon Dioxide Laser

다국어 초록 (Multilingual Abstract)

Carbon dioxide (CO2) laser is one of the most widely used lasers in dermatology. CO2 laser can precisely ablate the skin with good hemostasis, which makes it an ideal surgical laser. With the development of pulsed CO2 laser, which enabled cleaner ablation with less residual thermal damage, CO2 laser resurfacing became the gold standard for skin rejuvenation. The rejuvenation effect of full-face CO2 laser resurfacing is unparalleled to other methods; however, it is associated with a relative high incidence of side effects and prolonged downtime. Fractional CO2 laser was developed to overcome this problem. With a new technology of fractionating the laser beam into hundreds of microbeams, fractional CO2 laser resurfacing can improve various skin conditions including skin laxity, photodamage, and acne scars with short downtime and significantly lesser side effects. For optimal treatment results, clinicians have to decide the treatment depth and density based on proper understanding of the laser tissue interaction and underlying skin conditions. (Korean J Dermatol 2016;54(4):233~240)

참고문헌 (Reference)

1 Tierney EP, "Treatment of lower eyelid rhytids and laxity with ablative fractionated carbon-dioxide laser resurfacing: Case series and review of the literature" 64 : 730-740, 2011

2 Tan J, "The use of the fractional CO2 laser resurfacing in the treatment of photoaging in Asians: five years long-term results" 46 : 750-756, 2014

3 Bernstein LJ, "The short- and long-term side effects of carbon dioxide laser resurfacing" 23 : 519-525, 1997

4 Shamsaldeen O, "The adverse events of deep fractional CO(2): a retrospective study of 490 treatments in 374 patients" 43 : 453-456, 2011

5 Omi T, "The Role of the CO2 Laser and Fractional CO2 Laser in Dermatology" 23 : 49-60, 2014

6 Kaplan I, "The CO2 surgical laser" 28 : 847-848, 2010

7 AlGhamdi K, "Successful treatment of atrophic facial leishmaniasis scars by co2 fractional laser" 18 : 379-384, 2014

8 Chapas AM, "Successful treatment of acneiform scarring with CO2 ablative fractional resurfacing" 40 : 381-386, 2008

9 Collawn SS, "Skin ultrastructure after CO2 laser resurfacing" 102 : 509-515, 1998

10 Naouri M, "Skin tightening induced by fractional CO(2) laser treatment: quantified assessment of variations in mechanical properties of the skin" 11 : 201-206, 2012

11 Graber EM, "Side effects and complications of fractional laser photothermolysis: experience with 961 treatments" 34 : 301-305, 2008

12 Anderson RR, "Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation" 220 : 524-527, 1983

13 Neri I, "Purpura after application of EMLA cream in two children" 22 : 566-568, 2005

14 Fitzpatrick RE, "Pulsed carbon dioxide laser resurfacing of photo-aged facial skin" 132 : 395-402, 1996

15 Fader DJ, "Principles of CO2/erbium laser safety" 26 : 235-239, 2000

16 Roldan-Marin R, "Petechial and purpuric eruption induced by lidocaine/prilocaine cream: a rare side effect" 8 : 287-288, 2009

17 Goldberg DJ, "Nonablative dermal remodeling: does it really work" 138 : 1366-1368, 2002

18 Dierickx CC, "Micro-fractional ablative skin resurfacing with two novel erbium laser systems" 40 : 113-123, 2008

19 Stier MF, "Laser treatment of pediatric vascular lesions: Port wine stains and hemangiomas" 58 : 261-285, 2008

20 Lowe NJ, "Laser skin resurfacing. Preand posttreatment guidelines" 21 : 1017-1019, 1995

21 Park SH, "Laser Dermatology Plastic Surgery" Koonja 2014

22 Carroll L, "LASER-tissue interactions" 24 : 2-7, 2006

23 Setyadi HG, "Infectious complications after nonablative fractional resurfacing treatment" 34 : 1595-1598, 2008

24 Hantash BM, "In vivo histological evaluation of a novel ablative fractional resurfacing device" 39 : 96-107, 2007

25 Avram MM, "Hypertrophic scarring of the neck following ablative fractional carbon dioxide laser resurfacing" 41 : 185-188, 2009

26 Shin MK, "Histologic comparison of microscopic treatment zones induced by fractional lasers and radiofrequency" 16 : 317-323, 2014

27 Ramsing NB, "Helix-coil transition of parallel-stranded DNA. Thermodynamics of hairpin and linear duplex oligonucleotides" 28 : 9528-9535, 1989

28 Metelitsa AI, "Fractionated laser skin resurfacing treatment complications: a review" 36 : 299-306, 2010

29 Hunzeker CM, "Fractionated CO2 laser resurfacing: our experience with more than 2000 treatments" 29 : 317-322, 2009

30 Manstein D, "Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury" 34 : 426-438, 2004

31 Bogdan Allemann I, "Fractional photothermolysis--an update" 25 : 137-144, 2010

32 Rahman Z, "Fractional deep dermal ablation induces tissue tightening" 41 : 78-86, 2009

33 Ma G, "Fractional carbon dioxide laserassisted drug delivery of topical timolol solution for the treatment of deep infantile hemangioma: a pilot study" 31 : 286-291, 2014

34 Song HS, "Fractional carbon dioxide laser-assisted photodynamic therapy for patients with actinic keratosis" 31 : 296-301, 2015

35 Groff WF, "Fractional carbon dioxide laser and plasmakinetic skin resurfacing" 27 : 239-251, 2008

36 Majid I, "Fractional CO2 Laser Resurfacing as Monotherapy in the Treatment of Atrophic Facial Acne Scars" 7 : 87-92, 2014

37 Ramsdell WM, "Fractional CO2 Laser Resurfacing Complications" 26 : 137-140, 2012

38 Ross EV, "Effects of overlap and pass number in CO2 laser skin resurfacing:a study of residual thermal damage, cell death, and wound healing" 24 : 103-112, 1999

39 Jung JY, "Early postoperative treatment of thyroidectomy scars using a fractional carbon dioxide laser" 37 : 217-223, 2011

40 Fife DJ, "Complications of fractional CO2 laser resurfacing: four cases" 41 : 179-184, 2009

41 Nanni CA, "Complications of carbon dioxide laser resurfacing. An evaluation of 500 patients" 24 : 315-320, 1998

42 Shin JU, "Comparison of non-ablative and ablative fractional laser treatments in a postoperative scar study" 46 : 741-749, 2014

43 The Korean Society for Aesthetic and Dermatologic Surgery, "Aesthetic and Dermatologic Surgery" Hanmi 2007

44 Chwalek J, "Ablative skin resurfacing" 42 : 40-47, 2011

45 Riggs K, "Ablative laser resurfacing: high-energy pulsed carbon dioxide and erbium:yttrium-aluminum-garnet" 25 : 462-473, 2007

46 Ortiz AE, "Ablative CO2 lasers for skin tightening: traditional versus fractional" 40 (40): S147-S151, 2014

47 Kauvar AN, "A histopathological comparison of “char-free” carbon dioxide lasers" 22 : 343-348, 1996

48 Kitzmiller WJ, "A controlled evaluation of dermabrasion versus CO2 laser resurfacing for the treatment of perioral wrinkles" 106 : 1366-1372, 2000