기능성 천연물 복합제의 이화학적 특성 확인

국문 초록 (Abstract)

혈압 강하를 목적으로 사용되는 천연물 복합제를 여러 문헌과 처방을 통해 선정하고, 기능성 식품 소재로의 이용 가능성을 검토할 목적으로 추출물의 이화학적 특성을 분석하였다. 천연물 복합제 28가지에 대한 추출물의 수율은 5.33～36.71% 범위를 나타내었고, 총 페놀 및 총 플라보노이드 함량은 204.89～2543.29 ㎎% 및 59.79～1430.55 ㎎% 범위를 나타내었으며, 특히 2, 5, 9, 17, 18, 20, 22 및 26번의 경우 800 ㎎% 이상의 높은 함량을 나타내었다. 전자공여능의 경우 7.81～98.18% 범위의 활성을 나타내었고, 전자공여능이 높게 나타난 시료는 총 페놀 및 총 플라보노이드 함량이 높게 나타났던 시료와 유사한 경향으로 확인되었으며, 이는 생약성분들인 페놀산과 플라보노이드가 중요한 항산화 역할을 하는 것으로 추정되었다. 아질산염 소거능의 경우 pH 1.2에서 11.70～96.47%, pH 4.2 및 6.0에서 각각 18.12% 및 12.77% 이하의 소거 효과를 나타내어, pH가 증가할수록 아질산염 소거작용은 감소하는 경향을 보여주었다. 더불어 천연물 복합제를 기능성 식품으로 이용가능성을 확인하기 위한 생물 활성의 평가도 체계적으로 연구되어야 하겠다.

다국어 초록 (Multilingual Abstract)

The herb mixtures that are known to lower blood pressure were selected through oriental medical books and prescriptions and the physicochemical properties of their water extracts were analyzed to examine the possibility as functional food materials. The total yield of 28 water extracts was in the range of 5.33～36.71%. Total phenolics and flavonoid content were 204.89～2543.29 ㎎% and 59.79～1430.55 ㎎%, respectively, and especially No. 2, 5, 9, 17, 18, 20, 22, and 26 showed high rates of above 800 ㎎%. Electron donating ability (EDA) was 7.81～98.18%, and the samples that showed high values in EDA were similar to the samples with high values in total phenolics and flavonoid content. Phenolics and flavonoid compounds of the herbs are considered to perform a major role in antioxidation. Nitrite scavenging ability reached the highest at pH 1.2 (11.70～96.47%) and the lowest at pH 6.0 (below 12.77%), which indicates that nitrite scavenging ability decreases when pH increases.

목차 (Table of Contents)

• Abstract
• 서론
• 재료 및 방법
• 결과 및 고찰
• 요약
• 문헌

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