Micro-CT를 이용한 백서 이소골 발생에 대한 연구 = Study on the Development of the Mouse Ossicles Using Micro-CT

다국어 초록 (Multilingual Abstract)

Background and Objectives：Detailed information on how ossicles change in the developing temporal bone would be helpful
in understanding biomechanical knowledge of ossicles. In this study, three dimensional structural images of mouse were investigated
through Micro-CT to understand developmental anatomy of its ossicles. Materials and Method：Thirty five temporal
bones of BALB/c mice, aged from gestational day 11 to postnatal day 21, and adults were investigated. Three-dimensional highresolution
reconstructions of the ossicles of the left sided temporal bones were obtained using a Micro-CT system. The right sided
temporal bones were used for the histological study. Results：Internal biomechanical characters (volume fraction, structure
model index, degree of anisotropy, etc) of murine ossicles and temporal bones were attained to the adult level at postnatal day 21.
Conclusion：This study will be useful in understanding the more accurate microstructure of murine temporal bone, and will provide
the anatomical basis for the future animal studies.

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