Very low protein plus ketoacid analogs of essential aminoacids do not confirm superiority of a low protein diet to retard chronic kidney disease progression

다국어 초록 (Multilingual Abstract)

I read with great interest the original work of Satirapoj et al [1], particularly with regard to the number of cases seen in patients affected by chronic kidney disease (CKD III and CKD IV). However, in spite of the use of an amino acid supplement, this study seems to lack clarity and provides no firm evidence by which to evaluate and confirm the aims of the study. In particular, I should like to emphasize the following: 1) There is no explanation as to how glomerular filtration rate (GFR) was calculated.

참고문헌 (Reference)

1 Bancha Satirapoj, "Very low protein diet plus ketoacid analogs of essential amino acids supplement to retard chronic kidney disease progression" 대한신장학회 37 (37): 384-392, 2018

2 Weiner ID, "Urea and ammonia metabolism and the control of renal nitrogen excretion" 10 : 1444-1458, 2015

3 Cupisti A, "Nutritional treatment of advanced CKD : twenty consensus statements" 31 : 457-473, 2018

4 Prokopienko AJ, "Microbiota-derived uremic retention solutes : perpetrators of altered nonrenal drug clearance in kidney disease" 11 : 71-82, 2018

5 Garneata L, "Ketoanalogue-supplemented vegetarian very low-protein diet and CKD progression" 27 : 2164-2176, 2016

6 Paes-Barreto JG, "Can renal nutrition education improve adherence to a low-protein diet in patients with stages 3 to 5 chronic kidney disease" 23 : 164-171, 2013

7 Sahathevan S, "Assessing protein energy wasting in a Malaysian haemodialysis population using self-reported appetite rating : a cross-sectional study" 16 : 99-, 2015

8 Fouque D, "Adherence to ketoacids/essential amino acids-supplemented low protein diets and new indications for patients with chronic kidney disease" 17 : 63-, 2016

9 Maroni BJ, "A method for estimating nitrogen intake of patients with chronic renal failure" 27 : 58-65, 1985