제주산 감귤꿀과 유채꿀의 항산화 및 멜라닌 생성 억제 효과

다국어 초록 (Multilingual Abstract)

In order to investigate the potential of Korean honey for whitening cosmetics, we prepared citrus blossom and oilseed rape honey from Jeju island in Korea. Citrus blossom and oilseed rape honey were showed antioxidant activities, such as 1,1-diphenyl-2-pycrylhydrazyl (DPPH) (IC<SUB>50</SUB>=29.25 and 41.5㎍/mL, respectivity) and 2,2′-azinobis-(3-ethyl-benzothiazoline-6-sulfonic acid) (ABTS) (IC50=38.25 and 59.25㎍/mL, respectivity). We measured their inhibitory effects on mushroom tyrosinase and melanin synthesis in B16F1. Both citrus blossom and oilseed rape honey were showed inhibitory activity higher than positive control, arbutin against mushroom tyrosinase. Citrus blossom and oilseed rape honey significantly prevented melanin production without effects on cell viability. When 25㎍/mL of citrus blossom and oilseed rape honey were applied, they reduced melanin contents of B16F1 melanoma cells about 62.25% and 70.25%, respectively. Therefore, this study suggests that citrus blossom and oilseed rape honey may be useful as a natural skin whitening agent.

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