세포외 기질의 구성 및 구조의 모방을 위한 바이오 빅데이터 시스템 설계 = Design of Bio-Big Data System to mimic the structure and structure of extracellular matrix

다국어 초록 (Multilingual Abstract)

The extracellular matrix provides the environment for cells and biochemical factors necessary for cell growth and differentiation. In the field of biomaterials, experiments have been continuing to make biomaterials that mimic the structure and structure of extracellular matrix, and use them to culture cells to produce tissues. However, it is necessary to analyze the constitution, structure, and characteristics of the extracellular matrix and to study the factors regulating the physical environment in order to produce a three-dimensional scaffold that differentiates cells into desired tissues, In this paper, we propose a bio-data system for storing and analyzing various data through extraction/processing from fluorescence-stained extracellular matrix images.

국문 초록 (Abstract)

세포외 기질은 세포가 성장하고 분화하는데 필요한 생화학적 인자들과 세포를 위한 환경을 제공한다. 생체재료 분야에서는 세포외 기질의 구성 및 구조를 모방한 생체재료를 만들고, 세포를 배양하여 조직을 만들어내는 실험이 지속되고 있다. 그러나 세포가 원하는 조직으로 잘 분화되는 3차원 지지체를 만들기 위해서는 세포외 기질에 대한 구성과 구조, 특성을 분석하고, 물리적 환경에 따른 조절 요인 등에 대한 연구가 필요하다.
본 논문에서는 형광 염색된 세포외 기질 이미지로부터 추출/가공을 통해 다양한 데이터를 저장하고 분석하는 바이오 빅데이터 시스템을 제안한다.

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