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      단일 족지 절단 환자의 상처 치유 위험인자에 대한 통계적 분석 = Statistical Analysis of the Risk Factors for Single Toe Amputation Patients in Wound Healing

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      https://www.riss.kr/link?id=A106087210

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      Purpose: This study compared and analyzed the risk factors that affect a wound healing group and healing failure group. Materials and Methods: From 2010 to 2018, 39 patients who had suffered a single toe amputation were evaluated retrospectively. The patients were divided into two groups (wound healing group and healing failure group - within at least 3 months following the amputation). Regarding the possible risk factors, age, gender, Wagner and Brodsky classifications, duration of diabetes mellitus, whether the patient had peripheral arterial occlusive disease (PAOD) or cardiovascular disease, body mass index, HbA1c, total cholesterol, estimated glomerular filtration rate (eGFR), blood urea nitrogen (BUN), smoking, and alcohol were investigated. Results: The mean duration of diabetes mellitus was 140 months in the healing group and 227 months in the healing failure group, and the duration of diabetes was significantly longer in the failure group (p=0.009). A significant difference in eGFR was observed between the two groups (59.17 mL/min/1.73 m2 in the healing group and 31.1 mL/min/1.73 m2 in the failure group) (p=0.022). Sixteen patients with PAOD were found, all 10 patients in the healing failure group were PAOD patients. Conclusion: To reduce the additional complications in single toe amputation patients, the underlying disease and appropriate treatment are the most important factors. In addition, a more proximal level of amputation also should be considered in cases of patients with PAOD, high BUN and low eGFR, and patients with long-term diabetes.
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      Purpose: This study compared and analyzed the risk factors that affect a wound healing group and healing failure group. Materials and Methods: From 2010 to 2018, 39 patients who had suffered a single toe amputation were evaluated retrospectively. The ...

      Purpose: This study compared and analyzed the risk factors that affect a wound healing group and healing failure group. Materials and Methods: From 2010 to 2018, 39 patients who had suffered a single toe amputation were evaluated retrospectively. The patients were divided into two groups (wound healing group and healing failure group - within at least 3 months following the amputation). Regarding the possible risk factors, age, gender, Wagner and Brodsky classifications, duration of diabetes mellitus, whether the patient had peripheral arterial occlusive disease (PAOD) or cardiovascular disease, body mass index, HbA1c, total cholesterol, estimated glomerular filtration rate (eGFR), blood urea nitrogen (BUN), smoking, and alcohol were investigated. Results: The mean duration of diabetes mellitus was 140 months in the healing group and 227 months in the healing failure group, and the duration of diabetes was significantly longer in the failure group (p=0.009). A significant difference in eGFR was observed between the two groups (59.17 mL/min/1.73 m2 in the healing group and 31.1 mL/min/1.73 m2 in the failure group) (p=0.022). Sixteen patients with PAOD were found, all 10 patients in the healing failure group were PAOD patients. Conclusion: To reduce the additional complications in single toe amputation patients, the underlying disease and appropriate treatment are the most important factors. In addition, a more proximal level of amputation also should be considered in cases of patients with PAOD, high BUN and low eGFR, and patients with long-term diabetes.

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      참고문헌 (Reference)

      1 권순효, "만성 콩팥병의 진단 및 검사" 대한내과학회 76 (76): 515-520, 2009

      2 Myerson MS, "Symposium : partial foot amputations" 29 : 139-142, 1994

      3 Miyajima S, "Risk factors for major limb amputations in diabetic foot gangrene patients" 71 : 272-279, 2006

      4 Singh N, "Preventing foot ulcers in patients with diabetes" 293 : 217-228, 2005

      5 Dickhaut SC, "Nutritional status : importance in predicting wound-healing after amputation" 66 : 71-75, 1984

      6 Sharp CS, "Microbiology of deep tissue in diabetic gangrene" 1 : 289-292, 1978

      7 Adler AI, "Lower-extremity amputation in diabetes. The independent effects of peripheral vascular disease, sensory neuropathy, and foot ulcers" 22 : 1029-1035, 1999

      8 Swaminathan A, "Lower extremity amputation in peripheral artery disease : improving patient outcomes" 10 : 417-424, 2014

      9 National Kidney Foundation, "K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification" 39 (39): S1-S266, 2002

      10 Nehler MR, "Intermediate-term outcome of primary digit amputations in patients with diabetes mellitus who have forefoot sepsis requiring hospitalization and presumed adequate circulatory status" 30 : 509-517, 1999

      1 권순효, "만성 콩팥병의 진단 및 검사" 대한내과학회 76 (76): 515-520, 2009

      2 Myerson MS, "Symposium : partial foot amputations" 29 : 139-142, 1994

      3 Miyajima S, "Risk factors for major limb amputations in diabetic foot gangrene patients" 71 : 272-279, 2006

      4 Singh N, "Preventing foot ulcers in patients with diabetes" 293 : 217-228, 2005

      5 Dickhaut SC, "Nutritional status : importance in predicting wound-healing after amputation" 66 : 71-75, 1984

      6 Sharp CS, "Microbiology of deep tissue in diabetic gangrene" 1 : 289-292, 1978

      7 Adler AI, "Lower-extremity amputation in diabetes. The independent effects of peripheral vascular disease, sensory neuropathy, and foot ulcers" 22 : 1029-1035, 1999

      8 Swaminathan A, "Lower extremity amputation in peripheral artery disease : improving patient outcomes" 10 : 417-424, 2014

      9 National Kidney Foundation, "K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification" 39 (39): S1-S266, 2002

      10 Nehler MR, "Intermediate-term outcome of primary digit amputations in patients with diabetes mellitus who have forefoot sepsis requiring hospitalization and presumed adequate circulatory status" 30 : 509-517, 1999

      11 Wagner FW Jr, "Instructional course lectures" C.V. Mosby 143-165, 1979

      12 Canaud L, "Infrainguinal cutting balloon angioplasty in de novo arterial lesions" 48 : 1182-1188, 2008

      13 Lee WC, "Influence of neuropathy and ischemia in the development and treatment of the diabetic foot" 34 : 749-753, 1999

      14 Creager MA, "Harrison's principles of internal medicine" McGraw-Hill Medical 2032-2033, 2012

      15 The DCCT Research Group, "Factors in development of diabetic neuropathy. Baseline analysis of neuropathy in feasibility phase of Diabetes Control and Complications Trial (DCCT)" 37 : 476-481, 1988

      16 Brodsky JW, "Evaluation of the diabetic foot" 48 : 289-303, 1999

      17 Maser RE, "Epidemiological correlates of diabetic neuropathy. Report from Pittsburgh Epidemiology of Diabetes Complications Study" 38 : 1456-1461, 1989

      18 배재익, "Endovascular Revascularization for Patients with Critical Limb Ischemia: Impact on Wound Healing and Long Term Clinical Results in 189 Limbs" 대한영상의학회 14 (14): 430-438, 2013

      19 Armstrong DG, "Classifying diabetic foot surgery : toward a rational definition" 20 : 329-331, 2003

      20 Roon AJ, "Below-knee amputation : a modern approach" 134 : 153-158, 1977

      21 Mayfield JA, "A foot risk classification system to predict diabetic amputation in Pima Indians" 19 : 704-709, 1996

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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
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