Controversial issues in radiotherapy for rectal cancer: a systematic review

다국어 초록 (Multilingual Abstract)

The role of radiotherapy (RT) as an adjuvant to surgical options in the treatment of locally advanced rectal cancer has been established as it reduces local recurrence when combined with surgical resection and enhances survival when used in multidisciplinary treatment. However, many issues need to be addressed; some of these can render RT unnecessary, whereas others can reveal a new role of RT in rectal cancer. This review will discuss not only the basic role of RT but also the associated but controversial issues in detail in an attempt to find answers and determine future directions for the next decade.

목차 (Table of Contents)

• Abstract
• Introduction
• Basic Role of Radiotherapy: Brief Review of Published Literature
• Should Radiotherapy Be Administered before or after Surgery?
• Is SCRT alone better than LCRT?
• Should Adjuvant Radiotherapy Be Recommended in All Rectal Cancer Patients or Only in T3N0 Cases of the Intermediate-Risk Group?
• Role of Radiotherapy in Incompletely Resected Cancers
• Optimal Interval between Radiotherapy and Surgery in the Preoperative Approach Its Effects on Oncologic Outcomes
• Complications due to Radiotherapy
• Organ Preservation with Radiotherapy
• Conclusion
• Conflict of Interest
• References