항암화학요법을 받고 있는 한국 대장암 환자의 삶의 질 영향 요인 = Factors Influencing Quality of Life during Chemotherapy for Colorectal Cancer Patients in South Korea

다국어 초록 (Multilingual Abstract)

Purpose: The purpose of this study was to investigate the levels of physical symptoms, anxiety, depression, and quality of life (QOL)during chemotherapy for colorectal cancer patients in South Korea and to identify factors influencing their QOL. Methods: Datawere collected from 144 colorectal cancer patients receiving chemotherapy during 2012 at one general hospital located in Seoul.
Physical symptoms were measured by the M. D. Anderson Symptom Inventory-Gastrointestinal Cancer Module, and anxiety and depressionwere measured by the Hospital Anxiety Depression Scale. QOL was measured by the Functional Assessment of Cancer Therapy-Colorectal. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Scheffé post hoc test, Pearson correlationand stepwise multiple regression. Results: Mean age of the participants was 56.6 and most of them were not employed. In terms ofcancer stage, 38.2% were in stage 3, followed by stage 4 (34.7%). The most frequent symptom was lack of appetite, followed bysleep disturbance and fatigue. The mean score for anxiety was 5.40 with a prevalence of 23% and that of depression 8.85 with aprevalence of 64.6%. The mean score for quality of life was 81.93 out of 136 and 75.3% of the variance in QOL was explained by depression,symptoms, anxiety, treatment place, and occupational status. Depression was the strongest predictive factor. Conclusion:Oncology professionals need to pay special attention to relieving depression as well as physical symptoms to improve QOL duringchemotherapy for colorectal cancer patients.

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