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      망막분지정맥폐쇄에서 황반부종 형태에 따른 유리체강내 베바시주맙 주입술 효과와 주입횟수 비교

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      다국어 초록 (Multilingual Abstract)

      Purpose: To compare the effects of intravitreal bevacizumab injection (IVB) in 3 types of macular edema secondary to branch retinal vein occlusion (BRVO). Methods: Patients with macular edema secondary to BRVO with at least 1-year follow-up after IVB were included in the present retrospective study. The authors classified the macular edema into 3 types according to OCT findings: diffuse macular edema (type 1), cystoid macular edema (type 2), and serous retinal detachment (type 3). The clinical outcome indicators were best corrected visual acuity, central macular thickness (CMT), and total number of injections. Results: The total injection number was significantly higher in type 2 than type 3 (p = 0.02). Changes in CMT were significantly different between type 2 and type 3 (p = 0.03). CMT decreased significantly after IVB in all types of macular edema. Conclusions: Morphologic classification of macular edema with OCT is useful for predicting efficacy of IVB in macular edema secondary to BRVO. J Korean Ophthalmol Soc 2012;53(8):1112-1117
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      Purpose: To compare the effects of intravitreal bevacizumab injection (IVB) in 3 types of macular edema secondary to branch retinal vein occlusion (BRVO). Methods: Patients with macular edema secondary to BRVO with at least 1-year follow-up after IVB ...

      Purpose: To compare the effects of intravitreal bevacizumab injection (IVB) in 3 types of macular edema secondary to branch retinal vein occlusion (BRVO). Methods: Patients with macular edema secondary to BRVO with at least 1-year follow-up after IVB were included in the present retrospective study. The authors classified the macular edema into 3 types according to OCT findings: diffuse macular edema (type 1), cystoid macular edema (type 2), and serous retinal detachment (type 3). The clinical outcome indicators were best corrected visual acuity, central macular thickness (CMT), and total number of injections. Results: The total injection number was significantly higher in type 2 than type 3 (p = 0.02). Changes in CMT were significantly different between type 2 and type 3 (p = 0.03). CMT decreased significantly after IVB in all types of macular edema. Conclusions: Morphologic classification of macular edema with OCT is useful for predicting efficacy of IVB in macular edema secondary to BRVO. J Korean Ophthalmol Soc 2012;53(8):1112-1117

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      참고문헌 (Reference)

      1 이승우, "망막분지정맥폐쇄환자에서 빛간섭단층계를 이용한 황반부종의 형태학적 관찰" 대한안과학회 46 (46): 969-975, 2005

      2 송영빈, "망막분지정맥폐쇄 황반부종에서 유리체강내 베바시주맙 주입술의 단기효과와 형태학적 분석" 대한안과학회 51 (51): 379-385, 2010

      3 Wu L, "Twelve-month safety of intravitreal injections of bevacizumab (Avastin): results of the Pan-American Collaborative Retina Study Group (PACORES)" 246 : 81-87, 2008

      4 Kang SW, "The correlation between fluorescein angiographic and optical coherence tomographic features in clinically significant diabetic macular edema" 137 : 313-322, 2004

      5 Gregori NZ, "Safety and efficacy of intravitreal bevacizumab (avastin) for the management of branch and hemiretinal vein occlusion" 29 : 913-925, 2009

      6 Rehák J., "Retinal vein occlusion. I. Pathogenesis of circulatory changes" 49 : 145-147, 1993

      7 Finkelstein D, "Retinal branch vein occlusion, In Retina, 1st ed" CV Mosby 1989

      8 Matsumoto Y, "Rebound macular edema following bevacizumab (Avastin) therapy for retinal venous occlusive disease" 27 : 426-431, 2007

      9 Hee MR, "Quantitative assessment of macular edema with optical coherence tomography" 113 : 1019-1029, 1995

      10 Brown GC, "Progressive capillary nonperfusion in temporal branch retinal vein obstruction" 21 : 290-293, 1989

      1 이승우, "망막분지정맥폐쇄환자에서 빛간섭단층계를 이용한 황반부종의 형태학적 관찰" 대한안과학회 46 (46): 969-975, 2005

      2 송영빈, "망막분지정맥폐쇄 황반부종에서 유리체강내 베바시주맙 주입술의 단기효과와 형태학적 분석" 대한안과학회 51 (51): 379-385, 2010

      3 Wu L, "Twelve-month safety of intravitreal injections of bevacizumab (Avastin): results of the Pan-American Collaborative Retina Study Group (PACORES)" 246 : 81-87, 2008

      4 Kang SW, "The correlation between fluorescein angiographic and optical coherence tomographic features in clinically significant diabetic macular edema" 137 : 313-322, 2004

      5 Gregori NZ, "Safety and efficacy of intravitreal bevacizumab (avastin) for the management of branch and hemiretinal vein occlusion" 29 : 913-925, 2009

      6 Rehák J., "Retinal vein occlusion. I. Pathogenesis of circulatory changes" 49 : 145-147, 1993

      7 Finkelstein D, "Retinal branch vein occlusion, In Retina, 1st ed" CV Mosby 1989

      8 Matsumoto Y, "Rebound macular edema following bevacizumab (Avastin) therapy for retinal venous occlusive disease" 27 : 426-431, 2007

      9 Hee MR, "Quantitative assessment of macular edema with optical coherence tomography" 113 : 1019-1029, 1995

      10 Brown GC, "Progressive capillary nonperfusion in temporal branch retinal vein obstruction" 21 : 290-293, 1989

      11 Otani T, "Patterns of diabetic macular edema with optical coherence tomography" 127 : 688-693, 1999

      12 Noma H, "Pathogenesis of macular edema with branch retinal vein occlusion and intraocular levels of vascular endothelial growth factor and interleukin-6" 140 : 256-261, 2005

      13 Nussenblatt RB, "Macular thickening and visual acuity. Measurement in patients with cystoid macular edema" 94 : 1134-1139, 1987

      14 Dick SB, "Macular edema, In Retina, 3rd ed" Mosby 55-57, 2001

      15 Gutman FA, "Macular edema secondary to occlusion of the retinal veins" 28 (28): 462-470, 1984

      16 Jalkh AE, "Macular edema in branch retinal vein occlusion: types and treatment" 20 : 26-32, 1989

      17 Finkelstein D., "Ischemic macular edema. Recognition and favorable natural history in branch vein occlusion" 110 : 1427-1434, 1992

      18 Tolentino MJ, "Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate" 103 : 1820-1828, 1996

      19 Noma H, "Intravitreal levels of vascular endothelial growth factor and interleukin-6 are correlated with macular edema in branch retinal vein occlusion" 244 : 309-315, 2006

      20 Rabena MD, "Intravitreal bevacizumab(Avastin) in the treatment of macular edema secondaryto branch retinal vein occlusion" 27 : 419-425, 2007

      21 Kreutzer TC, "Intravitreal bevacizumab for the treatment of macular oedema secondary to branch retinal vein occlusion" 92 : 351-355, 2008

      22 Rabena MD, "Intravitreal bevacizumab (Avastin) in the treatment of macular edema secondary to branch retinal vein occlusion" 27 : 419-425, 2007

      23 Funk M, "Intraocular concentrations of growth factors and cytokines in retinal vein occlusion and the effect of therapy with bevacizumab" 50 : 1025-1032, 2009

      24 Antcliff RJ, "Comparison between optical coherence tomography and fundus fluorescein angiography for the detection of cystoid macular edema in patients with uveitis" 107 : 593-599, 2000

      25 Jonas JB, "Branch retinal vein occlusion treated by intravitreal triamcinolone acetonide" 19 : 65-71, 2005

      26 "Argon laser photocoagulation for macular edema in branch vein occlusion. The Branch Vein Occlusion Study Group" 98 : 271-282, 1984

      27 "Argon laser photocoagulation for macular edema in branch vein occlusion. The Branch Vein Occlusion Study Group" 98 : 271-282, 1984

      28 Weinberg D, "Anatomy of arteriovenous crossings in branch retinal vein occlusion" 109 : 298-302, 1990

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      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2017-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2013-01-01 평가 등재 1차 FAIL (등재유지) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2007-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2006-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2005-01-01 평가 등재후보학술지 유지 (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.22 0.22 0.22
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.23 0.23 0.366 0.02
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