국내 발생 돼지 구제역의 임상증상, 육안병변 및 현미경적 병변 = Clinical Signs and Pathologic Lesions of Foot and Mouth Disease in Pigs, Korea

다국어 초록 (Multilingual Abstract)

We described the clinical signs, gross lesions, histopathological lesions, and electronmicroscopy of pig Foot-and-
Mouth Disease cases which had occurred in 2002, Korea. Grossly affected pigs showed vesicles on snout, tongue, coronary
band, and udder. Histoapthologically, severe intercellular edema and necrosis of prickle cells, and separation between
epidermis and dermis were found on the mucosa of tongue and coronary band. And myocardial necrosis and mononuclear
cells infiltration in myocardium were found. Electronmicroscopically numerous picornavirus particles(18~22 nm in diameter)
were found in the cytoplasm of prickle cells. By those results, we confirm that those cases were typical FMD cases.

참고문헌 (Reference)

1 "The pathogenesis of natural and simulated Foot-and-Mouth Disease infection in cattle" 599-609,

2 "Pathology of Domestic Animals" Academic Press Inc me 2 : 141-144, 1991

3 "Pathogenesis of Foot-and- Mouth Disease in Swine Studied by In-situ Hybridization" 113 : 51-58, 1995

4 "Natural adaption to pigs of a Taiwanese isolate of foot-and-mouth disease virus" 141 : 174-175, 1997

5 "Morphogenesis of Vesiculation in Foot-and-Mouth Disease" 1537-1542,

6 "In vivo characterization and transmission of Korean foot-and-mouth disease virus(FMDV)" 40 : 719-727, 2000

7 "Hagan and Bruner's Microbiology and Infectious Diseases of Domestic Animals" Ithaca and London Comstock Publishing Associates 674-676, 1988

8 "Hagan and Bruner's Microbiology and Infectious Diseases of Domestic Animals" Ithaca and London Comstock Publishing Associates 647-667, 1988

9 "Hagan and Bruner's Microbiology and Infectious Diseases of Domestic Animals" Ithaca and London Comstock Publishing Associates 846-851, 1988

10 "Disease caused by Apthovirus In: Veterinary Pathology" Williams & Wilkins 1 : 271-273, 1997

11 "A Recent History of Foot-and-Mouth Disease" 118 : 89-108, 1998

12 "A Pathogenesis Study of Foot-and-Mouth Disease in Cattle Using in situ Hybridization" 189-193