쇼그렌 증후군을 동반한 자가 면역성 만성 췌장염 1예 = A case of autoimmune chronic pancreatitis associated with sjo¨gren's syndrome

국문 초록 (Abstract)

저자 등은 쇼그렌 증후군을 동반한 자가 면역성 만성 췌장염 증례를 국내 최초로 보고하면서 스테로이드 경구 복용 후에 자가 면역성 만성 췌장염 뿐만 아니라 쇼그렌 증후군의 임상양상도 호전되었다는 점에서 매우 의미있는 증례로 판단하여 문헌고찰과 함께 본 증례를 보고한다.

다국어 초록 (Multilingual Abstract)

We report a case of autoimmune chronic pancreatitis associated with Sjogren's syndrome. A68-year-old man was admitted to the hospital with jaundice. The serum IgG and IgE were elevated and endoscopic retrograde cholangipancreatography demonstrated an irregular narrowing of the main pancreatic duct and stricture of the distal common bile duct. He complained of dry mouth and dry eyes with a gritty feeling. On physical examination, enlargement of both submandibular glands was noted. Schirmer test revealed positive result and the labial minor salivary gland biopsy showed infiltration of lymphocytes and plasma cells, consistent with Sjogren's syndrome. After one month of oral steroid therapy, the abnormalities in clinical, laboratory and radiological findings of autoimmune chronic pancreatitis were improved markedly. The enlargement of both submandibular glands was improved, too.
To our knowledge, this is the first case of autoimmune chronic pancreatitis associated with Sjogren's syndrome in Korea.

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