제 2형 당뇨병 환자의 흡연여부에 따른 당화혈색소와 당뇨병성 만성합병증 = Glycated Hemoglobins and Chronic Complications of Diabetes Mellitus, based on the Smoking Status of Patients with Type 2 Diabetes Mellitus

다국어 초록 (Multilingual Abstract)

Purpose: This research seeks to identify differences between general characteristics, disease-related characteristics, glycated hemoglobin (HbAlc) levels, and aspects of chronic complications of diabetes mellitus in type 2 diabetes. Methods: This research was conducted from the 1st to the 15th of February in 2016, on 263 in patients. Patients' electronic medical records were used to identify their general characteristics, disease-related characteristics, HbAlc, and chronic diabetic complications. Chi-square test, ANOVA, ANCOVA, and the Cochran-Mantel-Haenszel test were used for data analysis. Results: Statistical significance was observed for general characteristics, based on smoking status, such as age, and education level; disease-related characteristics differed according to the duration of diabetes. Smoking status did not differ according to HbAlc level. In term of chronic diabetic complications, statistically significance was observed for diabetic nephropathy, based on smoking status. Conclusion: Patients who had a history of smoking, but were not currently smoking, were likely to display higher HbAlc levels and diabetic nephropathy. Therefore, there is need for regular checkups for diabetic complications among patients with a history of smoking and it is important to emphasize smoking cessation.

참고문헌 (Reference)

1 이용제, "흡연 정도에 따른 백혈구 수 증가와 고혈당증의 관계" 대한가정의학회 28 (28): 32-38, 2007

2 김희승, "제2형 당뇨병환자 성별 대사증후군 유병률과 위험요인 차이" 성인간호학회 18 (18): 3-9, 2006

3 홍상모, "제2형 당뇨병 환자에서의 당뇨병성 망막증과 대혈관 합병증과의 관계" 대한내과학회 81 (81): 351-358, 2011

4 박창해, "우리나라 성인 남성에서 흡연량과 공복혈당장애 또는 제2형 당뇨병 발생과의 연관성" 대한예방의학회 41 (41): 249-254, 2008

5 최정수, "고혈압․당뇨 관리와 흡연 및 음주행태의 관련성 분석연구" 한국보건사회연구원 27 (27): 103-130, 2007

6 Keith, R. J, "Tobacco use, insulin resistance, and risk of type 2diabetes: results from the multi-ethnic study of atherosclerosis" 11 (11): e0157592-, 2016

7 Jose, M. J, "The role of smoking as a modifiable risk factor in diabetic nephropahty" 64 (64): 34-38, 2016

8 Park, Y. J, "The relationship between the symptom of the peripehral polyneuropathy and smoking among the diabetic patients" 15 (15): 199-207, 1994

9 Ryu, J. H, "The prevalence and risk factors of peripheral arterial disease with type 2 DM" Ulsan University 2010

10 Blomster, J. I, "The harms of smoking and benefits of smoking cessation in women compared with men with type 2diabetes: an observational analysis of the ADVANCE(action in diabetes and vascular disease: preterax and diamicron midified release controlled evaluation) trial" 6 (6): e009668-, 2016

11 Song, M. S, "The degree of glycemic control and chronic complications development by compliance of health care regimen for type 2 diabetes mellitus patients" Catholic University 2002

12 염형선, "The Association Between Smoking Tobacco After a Diagnosis of Diabetes and the Prevalence of Diabetic Nephropathy in the Korean Male Population" 대한예방의학회 49 (49): 108-117, 2016

13 Nilsson, P. M, "Steering committee of the swedish national diabetes Register. Smoking is associated with increased HbA1C values and microalbuminuria in patients with diabetes-data from the National Diabetes Register in Sweden" 30 (30): 261-268, 2004

14 Boudec, J. L, "Smoking cessation and the incidence of pre-diabetes and type 2 diabetes : a cohort study" 30 (30): 43-48, 2016

15 Hur, N, W, "Smoking cessation and risk of type 2diabetes mellitus: Korean Medical Insurance Corporation Study" 14 (14): 244-249, 2007

16 Althouse, A. D, "Risk factors for incident peripheral arterial disease in type 2 diabetes; results from the bypass angioplasty revascularization investigation in type 2 Diabets(BARI 2D)Trial" 37 (37): 1346-1352, 2014

17 Pan, A, "Relation of smoking with total mortality and cardiovascular events among patients with diabetes mellitus. A meta-analysis and systematic review" 132 (132): 1795-1804, 2015

18 Pinto, N. R, "Nephropathy among type Ⅱ diabetes at a rural health centre, Goa, Inida" 3 (3): 555-558, 2016

19 Ministry of Health and Welfare, "Korea Health Statistics 2014 : Korea National Health and Nutrition Examination Survey (KNHANES VI-2)" Korea National Health and Nutrition Examination Survey

20 Soo Geun Kim, "Incidence and Risk Factors of Insulin Resistance Syndrome in 20-59 Year-Old Korean Male Workers" 대한의학회 22 (22): 968-972, 2007

21 Faul, F, "G*Power 3 : a flexible statistical power analysis program for the social, behavior, and biomedical sciences" 39 (39): 175-191, 2007

22 Kim, S. G, "Epidemiology and current Status of diabetes in Korea" 29 (29): 122-129, 2009

23 Ohkuma, T, "Effects of smoking and its cessation on creatinine- and cystatin C-based estimated glomerular filtration rates and albuminuria in male patients with type 2 diabetes mellitus: the Fukuoka Diabetes Registry" 2016

24 Kallio, M, "Development of new peripheral arterial occlusive disease in patients with type 2 diabetes during a mean follow-up of 11 years" 26 (26): 1241-1245, 2003

25 Chase, H. P, "Cigarette smoking increases the risk of albuminuria among subjects with Type ⅠDiabetes" 265 (265): 614-617, 1991

26 Will, J. C, "Cigarette smoking and diabetes mellitus : evidence of a positive association from a large prospective cohort study" 30 (30): 540-546, 2001

27 Eliasson, B, "Cigarette smoking and diabetes" 45 (45): 405-413, 2003

28 Okada, K, "Ankle-brachial index and eicosapentaenoic acid/arachidonic acid ratio in smokers with type 2 diabetes mellitus" 14 : 2-, 2016