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    참전복(Haliotis discus hannai) Myostatin 유전자의 cDNA 동정 및 발현 분석 = Molecular Cloning and Expression Pattern of Abalone (Haliotis discus hannai) Myostatin cDNA

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    https://www.riss.kr/link?id=A103871313

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    We cloned and sequenced the open reading frame (ORF) cDNA encoding myostatin from the muscle of abalone (Haliotis discus hannai). The ORF cDNA of the abalone myostatin is 1134 bp and encoded 377 amino acid residues that were 60-96% homologous with the amino acids of other organism myostatins. In addition, the ORF contained a conserved proteolytic cleavage site (RXRR) and nine conserved cysteine residues in the C-terminus. Semi-quantitative RT-PCR revealed the presence of myostatin mRNA in various tissues. The strongest expression was observed in the mantle of female abalone, and the gills and heart of male abalone.
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    We cloned and sequenced the open reading frame (ORF) cDNA encoding myostatin from the muscle of abalone (Haliotis discus hannai). The ORF cDNA of the abalone myostatin is 1134 bp and encoded 377 amino acid residues that were 60-96% homologous with the...

    We cloned and sequenced the open reading frame (ORF) cDNA encoding myostatin from the muscle of abalone (Haliotis discus hannai). The ORF cDNA of the abalone myostatin is 1134 bp and encoded 377 amino acid residues that were 60-96% homologous with the amino acids of other organism myostatins. In addition, the ORF contained a conserved proteolytic cleavage site (RXRR) and nine conserved cysteine residues in the C-terminus. Semi-quantitative RT-PCR revealed the presence of myostatin mRNA in various tissues. The strongest expression was observed in the mantle of female abalone, and the gills and heart of male abalone.

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    참고문헌 (Reference)

    1 Amali, A.A, "Up-regulation of muscle-specific transcription factors during embryonic somitogenesis of zebrafish (Danio rerio) by knock-down of myo- statin-1" 229 : 847-856, 2004

    2 Kocamis, H, "The ontogeny of myostatin, follistatin andactivin-B mRNA expression during chicken embryonic development" 63 : 143-150, 1999

    3 Biga, P.R, "The isolation,characterization,and expression of a novel GDF11 gene and a second myostatin form in zebrafish,Danio rerio.Comp.Biochem.Physiol.B Biochem.Mol.Biol.,141,218-230" 141 : 218-230, 2005

    4 Delgado, I, "Temporal and spatial expression pattern of the myostatin gene during larval and juvenile stages of the Chilean flounder (Paralichthys adspersus)" 151 : 197-202, 2008

    5 McPherron, A.C, "Suppression of body fat accumulation in myostatin deficient mice" 109 : 595-601, 2002

    6 Gonzalez-Cadavid, N.F, "Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting" 95 : 14938-14943, 1998

    7 Sharma, M, "Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct" 180 : 1-9, 1999

    8 Tomas, M, "Myostatin, a Negative Regulator of Muscle Growth, Functions by Inhibiting Myoblast Proliferation" 275 : 40235-40243, 2000

    9 Robert, S.B, "Myostatin protein and RNA transcript levels in adult and developing brook trout" 210 : 9-20, 2003

    10 Lin, J, "Myostatin knockout in mice increases myogenesis and decreases adipogenesis" 291 : 701-706, 2002

    1 Amali, A.A, "Up-regulation of muscle-specific transcription factors during embryonic somitogenesis of zebrafish (Danio rerio) by knock-down of myo- statin-1" 229 : 847-856, 2004

    2 Kocamis, H, "The ontogeny of myostatin, follistatin andactivin-B mRNA expression during chicken embryonic development" 63 : 143-150, 1999

    3 Biga, P.R, "The isolation,characterization,and expression of a novel GDF11 gene and a second myostatin form in zebrafish,Danio rerio.Comp.Biochem.Physiol.B Biochem.Mol.Biol.,141,218-230" 141 : 218-230, 2005

    4 Delgado, I, "Temporal and spatial expression pattern of the myostatin gene during larval and juvenile stages of the Chilean flounder (Paralichthys adspersus)" 151 : 197-202, 2008

    5 McPherron, A.C, "Suppression of body fat accumulation in myostatin deficient mice" 109 : 595-601, 2002

    6 Gonzalez-Cadavid, N.F, "Organization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wasting" 95 : 14938-14943, 1998

    7 Sharma, M, "Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct" 180 : 1-9, 1999

    8 Tomas, M, "Myostatin, a Negative Regulator of Muscle Growth, Functions by Inhibiting Myoblast Proliferation" 275 : 40235-40243, 2000

    9 Robert, S.B, "Myostatin protein and RNA transcript levels in adult and developing brook trout" 210 : 9-20, 2003

    10 Lin, J, "Myostatin knockout in mice increases myogenesis and decreases adipogenesis" 291 : 701-706, 2002

    11 Acosta, J, "Myostatin gene silenced by RNAi show a zebrafish giant phenotype" 119 : 324-331, 2005

    12 Kambadur, R, "Mutations in myostatin (GDF8) in double-muscled Belgian blue and Piedmontese cattle" 7 : 910-916, 1977

    13 Chenna, R, "Multiple sequence alignment with the clustal series of pro- grams" 31 : 3497-3500,

    14 Sambrook, T, "Molecular Cloning: A Laboratory Manual" Cold Spring Habor Laboratory Press 1989

    15 Kumar, S, "MEGA3: Integrated software for molecular evolutionary genetics analysis and sequence alignment" 5 : 150-163, 2004

    16 McPherron, A.C, "Double muscling in cattle due to mutations in the myostatin gene" 64 : 12457-12461, 1997

    17 Lee, S.B, "Characterization and expression pattern of the partial myostatin cDNA in shrimp" 2 : 224-229, 2007

    18 Hall,T.A, "BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT" 41 : 95-98, 1999

    19 Xu, C, "Analysis of myostatin gene structure, expression and function in zebrafish" 206 : 4067-4079, 2003

    20 Kimurá,M, "A simple method for estimating evolutionary rate of base substitution through com- parative studies of nucleotide sequences" 16 : 116-120, 1980

    21 Grobet, L, "A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle" 17 : 71-74, 1997

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    학술지 이력

    학술지 이력
    연월일 이력구분 이력상세 등재구분
    2026 평가 재인증평가 신청대상 (재인증)
    2020-01-01 등재 등재학술지 유지 (재인증) KCI등재
    2017-01-01 등재 등재학술지 유지 (계속평가) KCI등재
    2014-08-06 학술지명변경 외국어명 : Korean Journal of Fisheries and Aquatic Sciences -> Korean Journal of Fisheries and Aquatic Sciences KCI등재
    2013-01-01 등재 등재학술지 유지 (계속평가) KCI등재
    2010-01-01 등재 등재학술지 유지 (등재유지) KCI등재
    2009-09-04 학회명변경 한글명 : 한국수산학회 -> 한국수산과학회
    영문명 : The Korean Fisheries Society -> The Korean Society of Fisheries and Aquatic Science
    KCI등재
    2009-07-03 학술지명변경 한글명 : 한국수산학회지 -> 한국수산과학회지
    외국어명 : Journal of The Korean Fisheries Society -> Korean Journal of Fisheries and Aquatic Sciences
    KCI등재
    2008-01-01 등재 등재학술지 유지 (등재유지) KCI등재
    2006-01-01 등재 등재학술지 유지 (등재유지) KCI등재
    2003-01-01 등재 등재학술지 선정 (등재후보2차) KCI등재
    2002-01-01 등재 등재후보 1차 PASS (등재후보1차) KCI등재후보
    1999-07-01 등재 등재후보학술지 선정 (신규평가) KCI등재후보
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    학술지 인용정보

    학술지 인용정보
    기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
    2016 0.47 0.47 0.43
    KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
    0.43 0.43 0.59 0.17
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