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      망막분지정맥폐쇄 황반부종에서의 유리체강내 트리암시놀론 주입술 후 시력호전의 예후인자 = Prognostic Factors after Intravitreal Triamcinolone Injection for Macular Edema due to Branch Retinal Vein Occlusion

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      https://www.riss.kr/link?id=A100524125

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      Purpose: To evaluate prognostic factors for improvement of visual acuity after intravitreal triamcinolone acetonide injection (IVTA) for treatment of macular edema (ME) secondary to branch retinal vein occlusion (BRVO). Methods: Sixty-eight eyes of 68...

      Purpose: To evaluate prognostic factors for improvement of visual acuity after intravitreal triamcinolone acetonide injection (IVTA) for treatment of macular edema (ME) secondary to branch retinal vein occlusion (BRVO). Methods: Sixty-eight eyes of 68 consecutive patients treated with IVTA for ME due to BRVO were retrospectively reviewed. Patients were categorized into 2 groups according to the final visual acuity. The ‘gainer group’ consisted of eyes with a gain of 2 or more Snellen chart lines and the ‘non-gainer group’ consisted of eyes with less than 2 lines improvement or which had worsened at the last follow-up visit. Comparative clinical characteristics and ophthalmoscopic examinations were analyzed between the 2 groups. Results: Out of the 68 eyes, 38 (56%) showed improved vision and were categorized as the gainer group; 30 eyes (44%) were categorized as the non-gainer group. The duration of symptoms in the non-gainer group was longer than the gainer group. Additionally, patients with a better baseline vision were expected to show greater improvement. The number of early visual acuity gainers who showed visual improvement at 1 month after IVTA was significantly higher in the gainer group. The number of eyes with angiographically documented macular ischemia was significantly higher in the non-gainer group. Existence of subretinal fluid has been identified as a positive factor for visual improvement. Conclusions: The cases with early treatment, good baseline visual acuity, case of favorable response to the initial IVTA, absence of macular ischemia, and baseline subretinal fluid are favorable prognostic factors for the outcome of visual acuity after IVTA for ME due to BRVO. J Korean Ophthalmol Soc 2012;53(1):49-58

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      참고문헌 (Reference)

      1 김호숭, "망막분지정맥폐쇄에 합병된 황반부종에서 유리체강내 트리암시놀론주입술과 베바시주맙주입술의 비교" 대한안과학회 51 (51): 1071-1076, 2010

      2 최창욱, "망막분지정맥폐쇄로 인한 황반부종에서 허혈성과 비허혈성 간의 유리체강내 스테로이드주사의 효과 차이" 대한안과학회 48 (48): 49-54, 2007

      3 Wilson CA, "Treatment with intravitreal steroid reduces blood-retinal barrier breakdown due to retinal photocoagulation" 110 : 1155-1159, 1992

      4 Yamaike N, "Three-dimensional imaging of cystoid macular edema in retinal vein occlusion" 115 : 355-362, 2008

      5 Domalpally A, "The standard care vs corticosteroid for retinal vein occlusion (SCORE) study system for evaluation of optical coherence tomograms: SCORE study report 4" 127 : 1461-1467, 2009

      6 Michels RG, "The natural course of retinal branch vein obstruction" 78 : 166-177, 1974

      7 Klein R, "The Wisconsin epidemiologic study of diabetic retinopathy. IV. Diabetic macular edema" 91 : 1464-1474, 1984

      8 Yamaguchi Y, "Serous macular detachment in branch retinal vein occlusion" 26 : 1029-1033, 2006

      9 Scott IU, "SCORE Study report1: baseline associations between central retinal thickness and visualacuity in patients with retinal vein occlusion" 116 : 504-512, 2009

      10 Shilling JS, "Retinal branch vein occlusion: a study of argon laser photocoagulation in the treatment of macular oedema" 68 : 196-198, 1984

      1 김호숭, "망막분지정맥폐쇄에 합병된 황반부종에서 유리체강내 트리암시놀론주입술과 베바시주맙주입술의 비교" 대한안과학회 51 (51): 1071-1076, 2010

      2 최창욱, "망막분지정맥폐쇄로 인한 황반부종에서 허혈성과 비허혈성 간의 유리체강내 스테로이드주사의 효과 차이" 대한안과학회 48 (48): 49-54, 2007

      3 Wilson CA, "Treatment with intravitreal steroid reduces blood-retinal barrier breakdown due to retinal photocoagulation" 110 : 1155-1159, 1992

      4 Yamaike N, "Three-dimensional imaging of cystoid macular edema in retinal vein occlusion" 115 : 355-362, 2008

      5 Domalpally A, "The standard care vs corticosteroid for retinal vein occlusion (SCORE) study system for evaluation of optical coherence tomograms: SCORE study report 4" 127 : 1461-1467, 2009

      6 Michels RG, "The natural course of retinal branch vein obstruction" 78 : 166-177, 1974

      7 Klein R, "The Wisconsin epidemiologic study of diabetic retinopathy. IV. Diabetic macular edema" 91 : 1464-1474, 1984

      8 Yamaguchi Y, "Serous macular detachment in branch retinal vein occlusion" 26 : 1029-1033, 2006

      9 Scott IU, "SCORE Study report1: baseline associations between central retinal thickness and visualacuity in patients with retinal vein occlusion" 116 : 504-512, 2009

      10 Shilling JS, "Retinal branch vein occlusion: a study of argon laser photocoagulation in the treatment of macular oedema" 68 : 196-198, 1984

      11 Campochiaro PA, "Ranibizumab for macular edema following branch retinal vein occlusion: six-month primary end point results of a phase Ⅲ study" 117 : 1102-1112, 2010

      12 Haller JA, "Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion" 117 : 1134-1146, 2010

      13 Chung EJ, "Prognostic factors for visual outcome after intravitreal bevacizumab for macular edema due to branch retinal vein occlusion" 246 : 1241-1247, 2008

      14 Shulman S, "Prognostic factors for visual acuity improvement after intravitreal triamcinolone injection" 21 : 1067-1070, 2007

      15 Jonas JB, "Predictive factors for visual acuity after intravitreal triamcinolone treatment for diabetic macular edema" 123 : 1338-1343, 2005

      16 Brasil OF, "Predictive factors for short-term visual outcome after intravitreal triamcinolone acetonide injection for diabetic macular oedema: an optical coherence tomography study" 91 : 761-765, 2007

      17 Jaissle GB, "Predictive factors for functional improvement after intravitreal bevacizumab therapy for macular edema due to branch retinal vein occlusion" 249 : 183-192, 2011

      18 Hoeh AE, "OCT patterns of macular edema and response to bevacizumab therapy in retinal vein occlusion" 248 : 1567-1572, 2010

      19 Marmor MF, "Mechanisms of fluid accumulation in retinal edema" 97 : 239-249, 1999

      20 Aref AA, "Management of macular edema secondary to branch retinal vein occlusion: an evidence-based update" 28 : 28-39, 2011

      21 Greer DV, "Macular oedema and retinal branch vein occlusion" 8 : 207-209, 1980

      22 Adamis AP, "Is diabetic retinopathy inflammatory disease?" 86 : 363-365, 2002

      23 Cekiç O, "Intravitreal triamcinolone injection for treatment of macular edema secondary to branch retinal vein occlusion" 25 : 851-855, 2005

      24 Negi AK, "Intravitreal triamcinolone improves vision in eyes with chronic diabetic macular oedema refractory to laser photocoagulation" 19 : 747-751, 2005

      25 Chen SD, "Intravitreal triamcinolone for the treatment of ischemic macular edema associated with branch retinal vein occlusion" 141 : 876-883, 2006

      26 Bashshur ZF, "Intravitreal triamcinolone for the management of macular edema due to nonischemic central retinal vein occlusion" 122 : 1137-1140, 2004

      27 Sutter FK, "Intravitreal triamcinolone for radiation-induced macular edema" 121 : 1491-1493, 2003

      28 Byun YJ, "Intravitreal triamcinolone acetonide versus bevacizumab therapy for macular edema associated with branch retinal vein occlusion" 248 : 963-971, 2010

      29 Ozkiris A, "Intravitreal triamcinolone acetonide for treatment of persistent macular oedema in branch retinal vein occlusion" 20 : 13-17, 2006

      30 Karacorlu M, "Intravitreal triamcinolone acetonide for the treatment of cystoid macular edema secondary to Behçet disease" 138 : 289-291, 2004

      31 Karacorlu M, "Intravitreal triamcinolone acetonide for the treatment of chronic pseudophakic cystoid macular oedema" 81 : 648-652, 2003

      32 Scott IU, "Intravitreal triamcinolone acetonide for idiopathic cystoid macular edema" 136 : 737-739, 2003

      33 Tao Y, "Intravitreal triamcinolone" 225 : 1-20, 2011

      34 Kondo M, "Intravitreal injection of bevacizumab for macular edema secondary to branch retinal vein occlusion: results after 12 months and multiple regression analysis" 29 : 1242-1248, 2009

      35 Nauck M, "Induction of vascular endothelial growth factor by platelet-activating factor and platelet-derived growth factor is downregulated by corticosteroids" 16 : 398-406, 1997

      36 Ota M, "Foveal photoreceptor layer in eyes with persistent cystoid macular edema associated with branch retinal vein occlusion" 145 : 273-280, 2008

      37 Shah SP, "Factors predicting outcome of vitrectomy for diabetic macular oedema: results of a prospective study" 90 : 33-36, 2006

      38 Joo Youn Oh, "Early versus Late Intravitreal Triamcinolone Acetonide for Macular Edema associated with Branch Retinal Vein Occlusion" 대한안과학회 21 (21): 18-20, 2007

      39 Jonas JB, "Duration of the effect of intravitreal triamcinolone acetonide as treatment for diffuse diabetic macular edema" 138 : 158-160, 2004

      40 Catier A, "Characterization of macular edema from various etiologies by optical coherence tomography" 140 : 200-206, 2005

      41 Russo V, "Bevacizumab compared with macular laser grid photocoagulation for cystoid macular edema in branch retinal vein occlusion" 29 : 511-515, 2009

      42 Scott IU, "Baseline predictors of visual acuity and retinal thickness outcomes in patients with retinal vein occlusion: Standard Care Versus COrticosteroid for REtinal Vein Occlusion Study report 10" 118 : 345-352, 2011

      43 "Argon laser photocoagulation for macular edema in branch vein occlusion. The Branch Vein Occlusion Study Group" 98 : 271-282, 1984

      44 Scott IU, "A randomized trial comparing the efficacy and safety of intravitreal triamcinolone with standard care to treat vision loss associated with macular edema secondary to branch retinal vein occlusion" 127 : 1115-1128, 2009

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      2016 0.22 0.22 0.22
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