P027 Pulsed dye laser treatment combined with oral minocycline for more than 4 weeks reduces recurrence rate of rosacea = P027 Pulsed dye laser treatment combined with oral minocycline for more than 4 weeks reduces recurrence rate of rosacea

다국어 초록 (Multilingual Abstract)

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다국어 초록 (Multilingual Abstract)

Background: Minocycline is one of the most commonly used agents for treatment of rosacea. Pulsed dye laser (PDL) has been suggested to be used adjunctively with oral and topical rosacea regimens for more effective symptom resolution. However, it is not known which treatment method can reduce the recurrence of rosacea effectively. Objectives: The primary objective was to identify whether 595nm-PDL treatment reduced recurrent rate among rosacea patients who were treated with oral minocycline. The secondary objective was to evaluate that the factors such as sex, age, rosacea type, topical agents, and the treatment duration with oral minocycline were associated with the hazard of recurrence of rosacea. Methods: 107 Korean patients with rosacea who started treatment with oral minocycline (100mg per day) with or without 595nm-PDL (total 2-4 sessions) between January 2013 and May 2015 were evaluated retrospectively. The follow-up period was 1 year from the end of the treatment. Results: The recurrence-free survival analysis revealed that the group with oral minocycline plus PDL was significantly different compared with the group with oral minocycline alone. Treatment of oral minocycline for 4 or less weeks without PDL remained a statistically significant risk factor compared with treatment of oral minocycline for more than 4 weeks with PDL. Conclusion: Pulsed dye laser can be used in combination with oral minocycline for more than 4 weeks to reduce relapses of rosacea.