Intradialytic exercise improves physical function and reduces intradialytic hypotension and depression in hemodialysis patients|RISS 상세보기

다국어 초록 (Multilingual Abstract)

Background/Aims: As numbers of maintenance hemodialysis patients are growing, debilitating conditions of muscle wasting and atrophy are becoming some of the greatest concerns in end-stage renal disease patients. Exercise training has various potential benefits in terms of prevention of a sustained decline in functional status. This study aimed to evaluate the physical, psychological, laboratory, and dialysis-related effects of intradialytic exercise.
Methods: We enrolled 22 patients from a hemodialysis center for a 6-month nonrandomized prospective trial. Combination of aerobic exercise with bicycle ergometer and anaerobic exercise with elastic bands was conducted during hemodialysis. Data including physical fitness test results, dialysis-related measurements, and biochemical laboratory results were collected at baseline, 3, and 6 months. Depression and quality of life were assessed using Beck Depression Inventory and Short Form-36 health survey.
Results: After exercise completion, there were significant improvements in back muscle power, forward and backward trunk flexibility, vertical jump, elbow flexion, sit to stand test, and 6-minute walk test (p < 0.05). No significant changes were observed in dry weight, blood pressure, Kt/V, and biochemical variables, except for intradialytic hypotension (p < 0.05). For depression, Beck Depression Inventory showed statistically significant enhancement (p < 0.05). Scores of Short Form-36 health survey did not show significant increase in each domain, except for bodily pain (p < 0.05).
Conclusions: Combined aerobic and anaerobic exercise training during dialysis was found to be effective on physical health status, intradialytic hypotension, and depression in terms of mental health. Therefore, the findings of the current study may provide an appropriate guidance for encouraging exercise by nephrologists.

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참고문헌 (Reference)

1 Saran R, "US Renal Data System 2015 Annual Data Report: epidemiology of kidney disease in the United States" 67 (67): S1-S305, 2016

2 Vaithilingam I, "Time and exercise improve phosphate removal in hemodialysis patients" 43 : 85-89, 2004

3 Yasuda T, "Thigh muscle size and vascular function after blood flow-restricted elastic band training in older women" 7 : 33595-33607, 2016

4 Falahi MJ, "The effect of intradialytic exercise on dialysis efficacy, serum phosphate, hemoglobin and blood pressure control and comparison between two exercise programs in hemodialysis patients" 26 : 152-161, 2008

5 Gratz A, "Self-estimated physical functioning poorly predicts actual exercise capacity in adolescents and adults with congenital heart disease" 30 : 497-504, 2009

6 Castaneda C, "Resistance training to reduce the malnutrition-inflammation complex syndrome of chronic kidney disease" 43 : 607-616, 2004

7 Carney RM, "Psychological effects of exercise training in hemodialysis patients" 33 : 179-181, 1983

8 Torino C, "Physical performance and clinical outcomes in dialysis patients : a secondary analysis of the EXCITE trial" 39 : 205-211, 2014

9 Painter P, "Physical functioning in end-stage renal disease patients : update 2005" 9 : 218-235, 2005

10 Sulowicz W, "Pathogenesis and treatment of dialysis hypotension" 70 : S36-S39, 2006