Acute viral hepatitis is a systemic infection affecting the liver predominantly. Almost all cases of acute viral hepatitis are caused by one of five viral agents; hepatitis A, B, C, D and E viruses. Clinical courses of viral hepatitis range from asymp...
Acute viral hepatitis is a systemic infection affecting the liver predominantly. Almost all cases of acute viral hepatitis are caused by one of five viral agents; hepatitis A, B, C, D and E viruses. Clinical courses of viral hepatitis range from asymptomatic to fulminant acute infections common to all types, on the one hand, and from subclinical persistent infections to rapidly progressive chronic liver disease with cirrhosis, common to the bloodborne types (HBV, HCV, and HDV), on the other. Toxin-induced and drug-induced hepatotoxicity, defined as any degree of liver injury caused by a drug or a toxic substance, is a frequent cause of acute liver injury and accounts for considerable portion of all cases of acute liver failure with hepatic encephalopathy.