鷄胎發生에 미치는 Dactinomycin의 影響에 對한 硏究 = The Effects of Dactinomycin on the Development of Chick Embryo

다국어 초록 (Multilingual Abstract)

The auther intend to analyze the effects of Dactinomycin on the weight gain of body and various organ of chick embryos.
On the 6th day of incubation, 1㎍ and 2㎍ of Dactinomycin were injected into the chorrioallantoic sac of each incubated egg of two groups.
Between the 12th day and 18th day of incubation, a daily total of thirty injected eggs of each group was broken for weighing the body weight and five organs- brain, heart, lung, liver and kidney of chick embryos. The effects of dose and differences of growth times were analyzed by Analysis of Variance and Coordinate System in Euclidean Three-space, and the determination of the significance in the levels of difference was made by the Turkey's Method. The formula applied to analyzing the data in growth is: y=a+bt+ct², in this formule y:growth quantity of embryo or organs, t:specific date of incubation period, a, b, c:constants.
The results are summarized as follows:
1. Dactinomycin suppressed growth of chick embryo and the growth inhibition appeared to be much stronger in the group of 2㎍ dosage than that of l㎍ dosage.
3. Growh rate was observed to be increased with incubatioon day in iung. liver, kidney of both dosages and brain of 1㎍ group and body weight, heart of 2㎍ injected group whereas body weight, heart of 1㎍ group and brain of 2㎍ group was decreased.
3. In the specific growth rate, the increase was in control group of lung and kidney of 2㎍ group, the others were decreased.
4. In the growth curve of associated three kind of organs, Dactinomycin injected group was showed with remarkable growth inhibition in order of dosages.
5. Curve pattern of each organ to vector size of associated two kind of organs: 1㎍ group showed ascending straight line most, descending straight line next, 2㎍ group showed ascending lower cenvex curve most, decending lower convex curve next control group has descending lower convex curve or ascending upper convex curve.