Triamcinolone 병변 내 주사로 호전된 비후성 원판상 홍반성 루푸스 = Short Report : Hypertrophic Lupus Erythematosus Successfully Treated with Triamcinolone Intralesional Injection

다국어 초록 (Multilingual Abstract)

Hypertrophic lupus erythematosus (HLE) is a distinct and rare clinical variant of chronic cutaneous lupus erythematosus (CCLE). It is characterized by verrucous lesions and a chronic course of disease. HLE tends to be much more refractory to treatment than classical CCLE. Therefore, the traditionally available therapeutic options including sun protection, topical and oral corticosteroids, hydroxychloroquine, retinoid and thalidomide are often unable to control the disease. We report here on the successful use of triamcinolone intralesional injection in a patient with HLE and who failed to respond to conventional treatment such as acitretin and hydroxychloroquine. (Korean J Dermatol 2010;48(12):1132∼1135)

참고문헌 (Reference)

1 서기석, "비후성 원판상 홍반성 루푸스 1예" 대한피부과학회 43 (43): 1388-1391, 2005

2 Uitto J, "Verrucous lesion in patients with discoid lupus erythematosus:clinical,histopathological and immunofluorescence studies" 98 : 507-520, 1978

3 Jue SJ, "Two cases of hypertrophic discoid erythemas in patients with chronic cutaneous lupus erythematosus" 39 : 834-836, 2001

4 de Berker D, "The sequelae of chronic cutaneous lupus erythematosus" 1 : 181-186, 1992

5 Newton R, "Molecular mechanisms of glucocorticoid action:what is important?" 55 : 603-613, 2000

6 Vinciullo C, "Hypertrophic lupus erythematosus:differentiation from squamous cell carcinoma" 27 : 76-82, 1986

7 Al-Mutairi N, "Hypertrophic lupus erythematosus treated successfully with acitretin as monotherapy" 32 : 482-486, 2005

8 Shimizu S, "Dramatic efficacy of oral aromatic retinoid in long-standing hypertrophic lupus erythematosus" 84 : 491-492, 2004

9 Sherman RN, "Cutaneous squamous cell carcinoma in black patients with chronic discoid lupus erythematosus" 32 : 677-679, 1993