한국인 대학생군 대상의 청.장년층 대사이상증후군 위험성 평가 = Evaluation of the Risk of Metabolic Syndrome for the Young Adults in Korean Students of a University

다국어 초록 (Multilingual Abstract)

Metabolic syndrome, defined as the clustering of several metabolic disorders including obesity (waist circumference ${\geq}90$ if male or ${\geq}80$ if female, cm), dyslipidemia ($TG{\geq}150$ or HDL-C<40 if male or <50 if female, mg/dl), hypertension ($BP{\geq}130/85mmHg$) and hyperglycemia (fasting plasma $glucose{\geq}110mg/dl$), increases the cardiovascular risk of the general population. Recently, risk of this syndrome arises in young adults world widely. Therefore, we randomly selected and evaluated the risk of metabolic syndrome of total 43 people (group I-22, group II-21) for 2 years. Group I was 22 peoples (15 males, 7 females) with age of 22 thru 35 year old (average 28 year old) and group II was 21 people (19 male, 2 female) with age of 22 thur 32 years old (average 24 year old) in Cheongju area from March 1st thru 30th of 2008 in Cheongju area from September 1st thru 30th of 2007 in order to find out how serious this phenomenon is in young adult of Korea. 13.95% (n=7) of total people has a metabolic syndrome by NCEP/ATPIII definition among this group (group I-6, group II-1). Those of 6 have 3 or over risk factor for metabolic syndrome such as obesity, hypertension, fasting blood glucose and hypetriglyceridemia at the same time (group I-5, group II-1). Group I have more risk factor because of more higher age than group II. Therefore we need aggressively to monitor and provide them for early diagnosis, educational programs and assistance for lifestyle changes in order to prevent metabolic syndrome among young adults.

참고문헌 (Reference)

1 Grassi, G, "and vascular stiffness: when body fat has an adverse impact on arterial dynamics" 23 : 1789-, 2005

2 "World Health Organization. Geneva, World Health Organization : Diet, nutrition and the prevention of chronic diseases: report of a joint WHO/FAO expert consultation" 916 : 2003

3 Reilly, M. P, "The metabolic syndrome: more than sum of its parts?" 108 : 1546-, 2003

4 "The US National Cholesterol Education Program (NCEP) Expert Panel: Third report of the National Cholesterol Education Program Expert Panel on Detection, Evalution, and Treatment of High Blood Cholesterol in Adults Adult Treatment Panel III (ATPIII) final report" 3143-, 2002

5 Westerbacka, J., "Resistance to acute insulin induced decreases in large artery stiffness accompanies the insulin resistance syndrome" 86 : 5262-, 2001

6 Kawamoto, R., "Relationship between serum uric acid concentration, metabolic syndrome and carotid atherosclerosis" 45 : 605-, 2006

7 Kosch, M., "Relationship between muscle sympathetic nerve activity and large artery mechanical vessel wall properties in renal transplant patients" 20 : 501-, 2002

8 Tapia Ceballos, L., "Prevalence of metabolic syndrome and its components in obese children and adolescents" 67 : 352-, 2007

9 WHO, "Physical status: The use and interpretation of anthropometry. WHO Technical Report Series" 1995

10 김현창, "Normal Serum Aminotransferase Levels and the Metabolic Syndrome: Korean National Health and Nutrition Examination Surveys" 연세대학교의과대학 47 (47): 542-550, 2006

11 Grandi, A. M., "Metabolic syndrome and morphofunctional characteristics of the left ventricle in clinically hypertensive nondiabetic subjects" 19 : 199-, 2006

12 Laaksonen, D. E, "Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study" 156 : 1070-, 2002

13 Scuteri, A., "Metabolic syndrome amplifies the ageassociated increases in vascular thckness and stiffness" 43 : 1388-, 2004

14 Malik, S., "Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults" 110 : 1245-, 2004

15 "Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel)" 285 : 2486-, 2001

16 Solymoss, B. C., "Effect of increasing metabolic syndrome score on atherosclertic risk profile and coronary artery disease angiogtaphic severity" 93 : 159-, 2004

17 Isomaa, B., "Cardiovascular morbidity and mortality associated with the metabolic syndrome" 24 : 683-, 2001