各種 胃手術後 Cortisone 이 胃液分泌에 미치는 影響에 關한 實驗的 硏究 = The Effect of Cortisone on the Gastric Secretion Following Various Gastric Operations

다국어 초록 (Multilingual Abstract)

Fourty dogs were used in this investigation, each ten of which were treated with gastrostomy, vagotomy, antrectomy and antrectomy with vagotomy. Two months postoperatively, free and total acidities and pepsin values of the gastric secretion were studied after administration of cortisone acetate, 0.5㎎. per Kg. of boly weight. Each sample was taken every 30 minutes 8 times following 12 hour fasting. Acidity was examined through To¨pfer Michaelis method and pepsin through Anson's-hemoglobin method.
The results obained were as follows:
1. In the vagotomy group, 84.9% reduction in free acidity, 62.0% reduction in total acidity and 64.4% reduction in pepsin value comparing with the values of cortisone stimulated control (gastrostomy) group. Whereas, in this vagotomy group, cortisone injection produced 16.9% increase in free acidity and 74.3% increase in total acidity but 0.4% decrease in pepsin values comparing with the value of preinjection resting state.
2. In the antrectomy group, 85.5% reduction in free acidity, 67.4% reduction in total acidity and 87.4% reduction in pepsin value comparing with the values of control group. Whereas, in this antrectomy group, cortisone infection produced 15.5% increase in total acidity and 1.2% increase in pepsin value but 7.4% decrease in free acidity comparing with the values of preinjection resting state.
3. In the antrectomy with vagotomy group, 98.5% reduction in free acidity, 83.1% reduction in total acidity and 85.9% reduction in pepsin value comparing with the values of cortisone stimulated control (gastrostomy) group. Whereas, in this antrectomy with vagotomy group, cortisone injection produced 83.3% decrease in free acidity, 42.1% decrease in total acidity and 46.9% decrease in pepsin value comparing with the values of preinjection resting state.

목차 (Table of Contents)

• Ⅰ. 緖論
• Ⅱ. 實驗材料 및 方法
• A. 實驗材料
• B. 胃液採取方法 및 胃液檢査法
• C. 手術方法
• Ⅲ. 實驗成績
• A. 正常對照群(胃瘻造設術)
• B. 迷走神經切斷術群
• C. 胃前庭部切除術群
• D. 胃前庭部切除 및 迷走神經切斷倂行施術群
• Ⅳ. 總括 및 考按
• Ⅴ. 結論
• 參考文獻