선천성기형에 대한 연구 = Clinical Study of the Congenital Anomalies

다국어 초록 (Multilingual Abstract)

This report was based on the 211 cases of the congenital anomalies of newborn infant among 22384 cases of deliversies from Jan. 1. 1981 to Dec. 31. 1990 at Ewha Womans University Hospital. The analyzed result were as follows; 1. The overall incidences of the congenital anomalies were 211 cased (0.96%) among 22384 cases of deliveries. 2. The incidence of congenital anomalies of over 35 year old group was 1.23%, that of 30-34 year old group was 1.04%, and that of 25-29 year old group was 1.02% and that of under 24 year old group was the lowest (0.46%). 3. The incidence of the congenital anomalies according to parity was the highest in the para 2 groups (1.09%), and that of nullipara group was 0.09% and that of para 1 group was 1.00% and that of over para 3 group was 0.91%. 4. The frequency of the congenital anomalies in male baby (1.00%) was slightly higher than that of female baby (0.88%). 5. The incidence of the congenital malformed premature babies (3.66%) was higher than that in matured babies (0.68%). 6. The incidences of the type of congenital anomalies was 23.2% in central nervous system, 21.8% in digestive system, 17.0% in multiple anomaly, 13.7% in musculoskeletal system, 11.3% in cardiovascular system and 3.3% in skin. 7. The incidence of the perinatal death of the congenital anomalies was the highest in the central nervous system (77.5%), and then the next incidence of multiple anomaly was 72.2%, and chromosomal anomaly 33.3%, musculoskletal anomaly 20.7%, digestive anomaly 17.4%, but none in skin anomaly and urogenital anomaly. 8. Among women who had delivered at least one baby with congenital anomaly, 4.3% of all women was abnormal in chromosomes and 43 women were exposed to adverse environmental factors. 39 cases of women had histories of taking various medications, especially herb drugs which took during the first trimester of pregnancy. But 73.9% of all women had shown unknown causes.