This experiment was undertaken to investigate calcium and magnesium metabolism of rats fed the diet containing two levels of calcium(0.05%, 0.1%) and magnesium (0.04%, 0.0002%).
Thirty-two males of Sprague-Dewley strain, 70-80g, were divided into 4 g...
This experiment was undertaken to investigate calcium and magnesium metabolism of rats fed the diet containing two levels of calcium(0.05%, 0.1%) and magnesium (0.04%, 0.0002%).
Thirty-two males of Sprague-Dewley strain, 70-80g, were divided into 4 groups and each group (8 rats) was fed ad libitum for 4 weeks. Calcium and magnesium in sera, tissues and femurs were determined by atomic absorption spectrophotometry.
The results obtained are summarized as follow. Net weight gain and feed efficiency ratio were decreased in the calcium and magnesium-deficient groups. The weights of liver, heart and kidney generally showed increasing tendency in the calcium-deficient group. Lung was showen to decrease in the magnesium-dificient group compared to the control group. Serum cholesterol
showed increasing tendency in the groups of deficiency in calcium and calcium plus magnesium.
Serum clacium and magnesium decreased in the groups of deficiency in calcium, magnesium and calcium plus magnesium. Calcium contents in liver and kindey were not affected by the dietary clacium and magnesium levels. Calcium contents in kidney were significantly increased in the groups of deficiency in magnesium levels. Calcium contents in kidney were significantly increased
in the groups of deficiency in magnesium and calcium plus magnesium.
Calcium contents in femur were decreased in the Calcium-deficient group, whereas magnesium contents in liver were increased in the magnesium-deficient group. Calcium and magnesiumexcretion to feces and urine was decreased in the calcium and magnesium deficient groups respectively.