절박유산 및 자궁외임신 진단시 혈청 beta-HCG의 2회 연속측정의 의의 = The Significance of Consecutive Measurements of Serum Levels of Beta-HCG in the

다국어 초록 (Multilingual Abstract)

Diagnosis of Threatened Abortion and Ectopic Pregnancy Recently, the consecutive measurements of serum levels of beta-HCG have been used in the diagnosis of the early complicated pregnancies such as threatened abortion, ectopic pregnancy, and missed abortion. To evaluate the differences of serum beta-HCG levels 48 hours apart in abnormal pregnancies, 23 cases of normal intrauterine pregnancies, 58 cases of threatened abortions, and 14 cases of ectopic pregnancies were studied. We measured two serum levels of beta-HCG consecutively 48 hours apart in each groups and compared the percent increase of the abnormal pregnancies with normal exponential curve of serum beta-HCG. The results were as follows: 1. The percent increase in normal intrauterine pregnancy, threatened abortion and ectopic pregnancy under the 9th gestational weeks were 49.8%, 26.4%, and -48.4%, respectively. 2. In the ectopic pregnancy, the initital levels of serum beta-HCG were much lower than those of normal intrauterine pregnancy and threatened abortion with the significant decrease of second levels(comparision of percent increase; P=0.015 and P=0.004, respectively) under the 9th gestational weeks. 3. In the threatened abortion, the initial levels of serum beta-HCG were similar with those of normal intrauterine pregnancy, but the percent increase were lower than those of normal intrauterine pregnancy(P=0.007), under the 9th gestational weeks.