신경성 폭식증 환자의 예후인자

다국어 초록 (Multilingual Abstract)

Objective：Over the last few years there has been growing concern about bulimia nervosa in Korea,
but there was only a few clinical study, especially about outcome and predictors. CBT combined with
pharmacotherapy has been recognized as the most effective short-term treatment modality, but there was
nonresponders. The purpose of this paper is to examine the factors that influence treatment response and
outcome in patients with bulimia nervosa. The identification of prognostic factors in bulimia nervosa will
help clinicians to deliver the most appropriate type of initial treatment to patients.
Method：The subjects were 62 patients from the outpatients of Mind & Mind psychiatric clinic,
who had been previously evaluated by EDI-2 and MMPI. The sociodemographic data, disease
progress, past history, family history, BMI, EDI-2 and MMPI were variables assessed. All patients
received a 12-week course of CBT combined with pharmacotherapy(fluoxetine 20-60mg/d). Responders
and non-responders group ware compared with each variables. Responders were defined as
patients who had maximum symptom frequencies of three or less during the last 4 weeks of treatment.
Result：Among 62 patients, responders were 32 and non-responders were 30. There was no
difference in sociodemographic variables such as age, education level, job, marriage. As a result of
comparing the two groups, non-responders were differentiated by their higher frequency of binge
eating·vomiting, history of suicide attempt, family history of psychiatric illness and use of laxatives or
diuretics. And among the subscale of EDI-2, there were significant high scores in bulimia, ineffectiveness,
interoceptive awareness.
Conclusion：The findings suggest that frequency of binge eating·vomiting, history of suicide
attempt, family history of psychiatric illness, and use of laxatives or diuretics could be prognostic
factors in patients with bulimia nervosa