알츠하이머형 치매 진단도구로써 한국판 캘리포니아 언어학습검사(K-CVLT)의 효용성 연구 = The Application of the Korean California Verbal Learning Test (K_CVLT) in the Diagnosis of Dementia of the Alzheimer type

다국어 초록 (Multilingual Abstract)

The aim of this investigation was to examine the clinical utility of the Korean California Verbal Learning Test (K-CVLT) as a staging measure for dementia.
The participants were 19 patients with Alzheimer's disease (AD) and 55 age- and education- comparable healthy control (HC) elderly adults who were sampled in Dongdaemun-Gu, Seoul.
The results of retrieval related quantitative indices revealed significant mean value differences between HC and AD groups. In the detailed comparison of quantitative indices which measured the process of memory, HC used more semantic clustering than AD. In comparing the serial position effect, AD's recent effects were remarkable than HC. The result of discriminant analysis showed that long term cued recall and recognition scores can be the most efficient indices for discriminating AD to HC with sensitivity and specificity.
These results suggest that the K-CVLT has clinical utility in the diagnosis for dementia of Alzheimer type.

국문 초록 (Abstract)

본 연구는 한국판 캘리포니아 언어학습검사(K-CVLT)가 치매진단검사로서 효용성을 가지고 있는지를 규명하기 위해 수행되었다. 환자집단은 경희의료원 한방병원 신경정신과 치매클리닉에 내원하는 환자 19명, 통제집단은 서울 동대문구에 거주하는 60세 이상의 정상노인 55명으로 구성되었다. 회상능력을 측정하는 K-CVLT 양적 척도의 대부분에서 두 집단간 유의미한 평균의 차이가 나타났으며, 기억과정을 측정하는 질적 척도의 비교에서는 정상집단이 환자집단에 비해 의미적 군집화를 많이 사용하는 것으로 나타났고, 계열위치 효과에서는 환자집단의 최신효과가 정상집단에 비해 두드러지는 것으로 밝혀졌다. 판별분석결과 장기단서회상과 재인이 두 집단을 가장 잘 변별해 줄 수 있는 변인으로 나타났으며, 민감도 78.9%, 특이도 85.5%, 판별정확률 83.8%로 나타났다. 연구결과를 통해 K-CVLT가 치매환자의 진단에 유용함이 확인되었다.

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