各種 腫瘍 患者에서의 血淸 ferritin에 對한 硏究 = Serum Ferritin Status in Patients with Various Malignancies

다국어 초록 (Multilingual Abstract)

Serum ferrtin, total hemogram, serum iron, total iron binding capacity and transferrin saturation were determined in 71 cases of various malignancies and 50 control subjects.
One case of colon cancer with liver metastasis showed greatest elevation in serum ferritin (1804ng/ml) and elevation of ferritin disproportionate to that of blood iron indices were found in 75%, 57.3%, 50.0%, 44.0%, 33.0%, 13.3% respectively of acute leukemia, lung cancer, colon cancer, hepatoma, lymphoma and stomach cancer.
Serum ferritinemia was in no relation with hemoglobin, serum iron, and transferrin saturation in each malignancy group.
Serum iron and transferrin saturation in stomach cancer group was significantly reduced to that of normal control. (p 0.01)
For evaluation of iron storage in malignancy patients, bone marrow iron staining rather than serum ferritin or serum iron profile is suggested.
Measurement and serial determination of serum ferritin and its isotypes (isoferritin) would be of value in the diagnosis and evaluation of response to treatment in malignant neoplasia.