고지방식이를 섭취한 난소절제 암컷 쥐의 수영운동이 백색지방조직의 항혈관신생에 미치는 효과 = Effect of swimming exercise on antiangiogenesis of white adipose tissue in highfat dietfed female ovariectomized mice

다국어 초록 (Multilingual Abstract)

This study investigated whether swimming exercises improves obesity through regulation of angiogenesis in white adipose tissue. Female mice with highfat diets were divided into shamoperated group (Sham), ovariectomized group (OVX), and swimtrained ovariectomized group (OVX + Swim). Compared to the Sham, OVX increased body weight, adipose tissue mass and size of adipocyte. However, these factors (: such as body weight, adipose tissue mass and size of adipocyte) of OVX + Swim decreased compared with OVX. Compared with the Sham, OVX increased the mRNA expression of angiogenic activator and MMPs and decreased the mRNA expression of angiogenic inhibitors in white adipose tissue. But OVX + Swim decreased the mRNA expression of angiogenic activator and MMPs and increased the mRNA expression of angiogenic inhibitors in white adipose tissue, compared with the OVX. Theses results suggested that swimming exercises the angiogenesis in white adipose tissue, resulting to improve obesity in highfat dietfed female OVX mice.

참고문헌 (Reference)

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