협심증환자에서 관동맥조영술상 관동맥병변의 진행 = Coronary Arteriographic Changes of the Atherosclerotic Coronary Arterial Lesion in Patients with Angina Pectoris

다국어 초록 (Multilingual Abstract)

Objectives: Identification of the coronary arterial lesion susceptible to accelerated progression of the atherosclerosis may provide important clinical information in the management of the patients with coronary artery diseases(CAD) or when revascularization procedures are planned especially in patients with multiple coroanry arterial lesions, We performed this study in order to evaluate 1) the changing pattems of coronary artery disease and 2) the possible factors for either progression or regression of the coronary arterial lesion in patients with angina pectors. Methods: 56 patients with angina pectoris who undertook repeated coronary arteriography (CAG) over an interval of 1 year or more were enrolled in the study. Patients who got PTCA, CABG, or thrombolytic therapy were excluded as well as vasospastic angina on initial coronary arteriography. Criteria for the progression and regression were the changes of the luminal narrowing of the coronary arterial segment by 20% or more, Results: Upon follow-up CAG, progression of the coronary arterial lesion was found in 55% of the patients, regression in 18% and no significant changes in 27%. Progression of the lesion was more frequently found in patients with multivessel disease and there was a tendency for new or prgressive lesion in the left anterior descending artery teritory than in any other coronary arteries. Among CAD risk factors, diabetes mellitus was more frequently associated with the progression of the coronary arterial lesion. Conclusion: The coronary arterial lesions in patients with angian pectoris are more frequently progressive rather than stationary or regressive, with a tendency for new or progressive lesion in the left anteior descending coroanry artery territory