韓國人의 肝炎B抗原分布 關한 硏究

다국어 초록 (Multilingual Abstract)

Acute viral hepatitis remains a rnajor worldwide public health problem. Epide'miologic and laboratory investigations indicate that 2 specific viruses are involved in this disease. The epidemiologic distinctiveness of these 2 viruses has recently been challenged. Viral hepatitis A, transrnitted primarily by the fecal-oral route, is also transmitted by the parenteral route. Viral hepatitis B occurs sporadically following parenteral inoculation of virus-infected blood products, although recent studies have deinonstrated that oral transinission can also occur. Distribution of Hepatitis B antigen (HB Ag) in Korean was investigated and the results are followings. 1. 3.1% out of 7,360 sera from paid blood donors of Korea University Woo-Suk hospital blood bank was HB Ag positive. In early stage of test, it was 5-10% but subsequently decreased gradually and was about 3% at the end of 1974. 2. The distribution of HB Ag in each age groups was investigated. The highest was in 11-20 age group (12. 7%) and 21-40 age group succeeded it. In sexual difference of it, male was twice as high as female in 11-20 age group but the difference was little in other age groups. The positive rate of antibody to HB Ag was the highest in 11-20 age group (2.7%) 3. Of 1,407 sera from out patients of Woo-Suk hospital, the distribution of HB Ag was the highest (9.8%) in the Department Gastrointestinal medicine and next was the Departments Chest surgery (9.5%) and Urology (7.8%) The distribution of hepatitis B antibody was the highest in General surgery (5.2%), Urology (4.7%) and next was Chest internal medicine (1.%) 4. The frequency of HB Ag in hlood donors from three blood banks in Seoul, positiveness was about 7% and out patients were 5.2%.