Administration of a subparalyzing of a nondepolarizing muscle relaxant (priming dose) prior to its indubating dose hastens the onset time of neuromuscular blockade.
This study was measured the optimal priming and intubating dose and time interval bet...
Administration of a subparalyzing of a nondepolarizing muscle relaxant (priming dose) prior to its indubating dose hastens the onset time of neuromuscular blockade.
This study was measured the optimal priming and intubating dose and time interval between these used doses of vecuronium during rapid sequence induction of Anesthesia.
We measured single-twich tension in 30 persons.
In group 1, of the study. the priming dose used 0.01mg. kg^-1 and thiopental sodium 5mg. kg^-1 i.v. four minutes after the priming dose. 0.1mg. kg^-1 i. v was given. onset times for the this group was significantly shorter than the other group.
In group Ⅱ. the priming dose were used 0.02mg. kg^-1 and thiopental sodium 5mg. kg^-1 i. v.
also, four minutes after the priming dose, 0.1mg. kg^-1 i. v was given. onset time for this group was induced as group I.
In group Ⅲ, the priming dose was not used. intubating dose 0.1mg. kg^-1 and thiopental sodium 5mg. kg -' i.v.
onset time for this group was significantly longer than the other groups. Intubating condition were silent and blood pressure. pulse rate and EKG were not change specially.