Fluoroquinolone계 항생제의 경구투여에 따른 양식넙치 및 조피볼락의 체내 잔류량의 변화 = Distribution Level of Fluoroquinolones in Olive flounder (Paralichthys olivaceus) and Black rockfish (Sebastes schlegeli) treated by Oral Administration

다국어 초록 (Multilingual Abstract)

The residue depletions of fluoroquinolones were investigated in the olive flounder (Paralichthys olivaceus) and black rockfish (Sebastes schlegeli) after 840 hours treatment with medicated feed at a dose 20 mg/kg·bw/day The bloods of samples were taken at 5, 10, 24, 48, 72, 120, 168, 216, 312, 480, 720, 840 and 960 hour after treatment. Fluoroquinolones concentrations were detected by high performance liquid chromatography equipped with UV detector. The recovery rates of fluoroquinolones in fish samples ranged 91.95~99.69%, 93.43~97.54% and 92.99~97.87% for the concentration of 0.1, 0.5, 1.0 ㎍/g, respectively In the blood of olive flounder, the concentrations of ciprofloxacin, enrofloxacin, norfloxacin and sarafloxacin detected at 10, 10, 24 and 24 hour after treatment were 6.433 ㎍/g, 6.065 ㎍/g, 11.8334 ㎍/g and 10.3168 ㎍/g as maximum level, respectively In the black rockfish, ciprofloxacin, enrofloxacin, norfloxacin and sarafloxacin at 24, 24, 24 and 10 hour after treatment were 8.2634㎍/g, 8.0276㎍/g, 7.2888㎍/g and 9.3787㎍/g as maximum level, respectively On the other hand, ciprofloxacin enrofloxacin, norfloxacin and sarafloxacin were not detected at 840, 480, 720 and 720 hours after treatment in the olive flounder, and at 720, 480, 720 and 480 hours after treatment in the black rockfish, respectiveley.