소아 뇌막염에서 뇌척수액의 LDH활성도, GOT치, Cholesterol치에 관한 연구 = A Prospective Study on LDH Activity, GOT and Cholesterol Levels in CSF of Patients with Meningitis in Children

국문 초록 (Abstract)

뇌막염에서 뇌척수액 내에 존재하는 각종 화학 성분 및 효소의 변화를 초래함은 잘 알려져 있다.
저자들은 이들 중 뇌척수액의 LDH 활성도, GOT치, Cholesterol치를 측정하여 이들의 진단적 가치와 치료 결과 판정에서의 유용성을 조사하였다.

다국어 초록 (Multilingual Abstract)

LDH activity, GOT and cholesterol levels in CSF were prospectively studied on 43 cases of patients with bacterial, aseptic and tuberculous types of meningitis and 11 cases of control group who were admitted to our department since June 1985.
The results obtained were as follows:
1.The LDH activity in CSF was significantly increased in patients with meningitis in all types compared with those of control group respectively (P<0.005). Among these the cases of bacterial meningitis revealed most prominent increment.
2.The LDH activity in CSF suggested a worthy role to differentiate bacterial meningitis from aseptic meningitis and also from tuberculous meningitis but in a lesser degree.
3.The GOT and cholesterol levels in CSF were significantly increased respectively in patients with bacterial meningitis compared with those of control group (P<0.005, P<0.025).
4.The GOT and cholesterol levels in CSF suggested a limited value for differential diagnosis of meningitides compared with those of LDH activity.
5.For the evaluation of treatment and prognosis, the LDH activity in CSF was relatively significant but those of GOT and cholesterol levels were not helpful.

목차 (Table of Contents)

• Ⅰ.서론
• Ⅱ.관찰 대상 및 방법
• 1.관찰 대상
• 2.방법
• Ⅲ.관찰 성적
• 1.LDH 활성도
• 2.GOT치
• 3.Cholesterol치
• 4.치료에 따른 뇌척수액 LDH활성도, GOT치, Cholesterol치의 변화
• Ⅳ.고찰
• Ⅴ.결론