소화성궤양 1,179 예에 대한 역학적 및 내시경적 고찰 = An Epidemiological and Endoscopic Study of Peptic Ulcer in 1,179 Cases소화성궤양 1,179 예에 대한 역학적 및 내시경적 고찰

다국어 초록 (Multilingual Abstract)

Several environmental factors are known to contribute to the development of peptic ulcer. The incidence and prevalence of peptic ulcer are changing along with changes in the environment. Therefore, we analyzed 1,179 prospective patients, who were diagnosed as peptic ulcer with gastrofiberscopy, in eight hospitals of Catholic University Medical College from August, 1988 to April, 1989. The results were as follows: 1) Of the 1,179 cases, the number of patients with duodenal ulcer was 606 (51.4%), with gastric ulcer 489 (41.5%), and with gastric ulcer and duodenal ulcer (combined ulcer) 84(7.1%). 2) The mean age of each group of patients with gastric ulcer, duodenal ulcer, and combined ulcer was 50.3±14.4 years, 39.6±12.7 years, and 47.9±13.0 years (p<0.005), respectively. The ratio of males to females was 3.4:1 in patients with gastric ulcer, 3.1:1 in patients with duodenal ulcer, and 4.3:1 in patients with combined ulcer. 3) The percentage of smokers was higher in patients with peptic ulcer (68.1% in patients with gastric ulcer, 58.9% in patients with duodenal ulcer and 69.0% in patients with combined ulcer) than the percentage of smokers in the general population(32%). 4) Blood type was not associated with incidence of peptic ulcer, but non-steroidal anti-inflammatory drugs and stressful stimuli may play a part in the genesis of peptic ulcer. 5) The incidence of peptic ulcer was characterized by regional variation and occupation. 6) The most common symptom was epigastric pain, but 3-4.5% in patients with pepetic ulcer had no complaints. 7) The most common shape of the ulcer was round or oval, and the most common aite was angle in gastric ulcer and anterior wall of bulb in duodenal ulcer. 8) The mean size was 1.4±1.0cm in gastric ulcer, 0.9±0.6 cm in duodenal ulcer, and 1.2±0.7 cm in combined ulcer (p<0.005). 9) The multiplicity of ulcers was 22.9% of gastric and 10.6% of duodenal ulcer.