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      전이성 거세-반응성 전립선암 치료의 현재 상황

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      https://www.riss.kr/link?id=A106817855

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      다국어 초록 (Multilingual Abstract)

      During last many decades, androgen deprivation therapy (ADT) was the main treatment of choice for metastatic castration-naïve prostate cancer (mCNPC). However, there are now more possible treatment options for mCNPC. In CHAARTED, GETUG-AFU 15, and STAMPEDE trial, docetaxel added to ADT improved overall survival compared to ADT alone in mCNPC. Also, STAMPEDE and LATITUDE trial revealed that abiraterone added to ADT improved overall survival compared to ADT alone for mCNPC patient. Furthermore, ARCHES and ENZAMET trial showed that enzalutamide added to ADT also can be a treatment option for mCNPC. Apalutamide added to ADT also improved survival compared to ADT alone in castration resistant prostate cancer patient. The usefulness of radiation therapy to primary tumor in mCNPC has also been studied in HORRAD and STAMPEDE trial. There are many ongoing trials for mCNPC setting. The aim of this paper is to review the current status of mCNPC management options.
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      During last many decades, androgen deprivation therapy (ADT) was the main treatment of choice for metastatic castration-naïve prostate cancer (mCNPC). However, there are now more possible treatment options for mCNPC. In CHAARTED, GETUG-AFU 15, and ST...

      During last many decades, androgen deprivation therapy (ADT) was the main treatment of choice for metastatic castration-naïve prostate cancer (mCNPC). However, there are now more possible treatment options for mCNPC. In CHAARTED, GETUG-AFU 15, and STAMPEDE trial, docetaxel added to ADT improved overall survival compared to ADT alone in mCNPC. Also, STAMPEDE and LATITUDE trial revealed that abiraterone added to ADT improved overall survival compared to ADT alone for mCNPC patient. Furthermore, ARCHES and ENZAMET trial showed that enzalutamide added to ADT also can be a treatment option for mCNPC. Apalutamide added to ADT also improved survival compared to ADT alone in castration resistant prostate cancer patient. The usefulness of radiation therapy to primary tumor in mCNPC has also been studied in HORRAD and STAMPEDE trial. There are many ongoing trials for mCNPC setting. The aim of this paper is to review the current status of mCNPC management options.

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      목차 (Table of Contents)

      • 서론
      • mCNPC에서 전신적 치료법
      • mCNPC에서 원발암에 대한 방사선요법
      • mCNPC에서 CYTOREDUCTIVE PROSTATECTOMY
      • OLIGOMETASTATIC mCNPC에서 METASTASIS DIRECTED THERAPY
      • 서론
      • mCNPC에서 전신적 치료법
      • mCNPC에서 원발암에 대한 방사선요법
      • mCNPC에서 CYTOREDUCTIVE PROSTATECTOMY
      • OLIGOMETASTATIC mCNPC에서 METASTASIS DIRECTED THERAPY
      • mCNPC에서 진행중인 연구들
      • 결론
      • REFERENCES
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