Since the liver distoma is caused by ingestion of the raw fresh water fish, determination of the resistance of the metacercariae present in those fishes is an important subject. Because Koreans use special seasonings in their cooking. The resistance o...
Since the liver distoma is caused by ingestion of the raw fresh water fish, determination of the resistance of the metacercariae present in those fishes is an important subject. Because Koreans use special seasonings in their cooking. The resistance of the metacercaria against several seasonings as well as other drugs has been determined.
1) Among the seasonings the metacercariae have the least resistance against garlic. They became immobile within 10 minutes in the filtrate of 1.0 gm of garlic in 1.0㏄. of water.
2) The metacercariae are quite resistant in the low temperature. They could survive for 40 hours in the temperature of 2℃ below zero and for 34 days in 2℃. However, they became immobile within one minute in the temperature above 55℃.
3) Among the antiprotozoas the metacercariae have a relatively weak resistance against Quinine and Atabrin but they are quite resistant against antibiotics such as streptomycin and Penicillin.
4) Among the drugs commonly used for the treatment of clonorchis the metacercariae have a weak resistance against Gentiana-Violot and Emetin but they are quite resistant against Antimon derivatives.