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      COVID-19 백신 접종 후 발생한 전신 부종에 대한 한양방 복합치료 치험 1례 = A Case of Generalized Edema in a Patient after COVID-19 Vaccination Improved by a Combined Korean-Western Medicine Approach

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      https://www.riss.kr/link?id=A108839921

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      다국어 초록 (Multilingual Abstract)

      Background: According to Vaccine Adverse Events Reporting System data, generalized edema followed by the COVID-19 vaccine is uncommon, with only 333 reported cases, and of those, 224 (69%) are associated with the Pfizer-BioNTech vaccine.
      Case report: A 76-year-old male patient with heart failure with preserved ejection fraction presented with spontaneous generalized edema and otherwise normal cardiac exams following administration of BNT162b2 (Pfizer-BioNTech) COVID-19 vaccination that had lasted for approximately 60 days and was treated successfully using Korean medicine treatment. After the administration of Korean medicine treatment, the patient’s symptoms in the bilateral limbs were dramatically controlled, without recurrence, for 2 months. As a result, generalized edema, which had been present for approximately 50 days, dramatically improved.
      Conclusion: This clinical case study suggests that a Korean medicine approach with Mokbangki-tang and Oryeong-san might be effective for the pleural effusion resolution of generalized edema after COVID-19 vaccination.
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      Background: According to Vaccine Adverse Events Reporting System data, generalized edema followed by the COVID-19 vaccine is uncommon, with only 333 reported cases, and of those, 224 (69%) are associated with the Pfizer-BioNTech vaccine. Case report: ...

      Background: According to Vaccine Adverse Events Reporting System data, generalized edema followed by the COVID-19 vaccine is uncommon, with only 333 reported cases, and of those, 224 (69%) are associated with the Pfizer-BioNTech vaccine.
      Case report: A 76-year-old male patient with heart failure with preserved ejection fraction presented with spontaneous generalized edema and otherwise normal cardiac exams following administration of BNT162b2 (Pfizer-BioNTech) COVID-19 vaccination that had lasted for approximately 60 days and was treated successfully using Korean medicine treatment. After the administration of Korean medicine treatment, the patient’s symptoms in the bilateral limbs were dramatically controlled, without recurrence, for 2 months. As a result, generalized edema, which had been present for approximately 50 days, dramatically improved.
      Conclusion: This clinical case study suggests that a Korean medicine approach with Mokbangki-tang and Oryeong-san might be effective for the pleural effusion resolution of generalized edema after COVID-19 vaccination.

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      참고문헌 (Reference)

      1 조은정, "코로나바이러스 감염증-19 백신 이상반응" 대한이비인후과학회 부산,울산,경남 지부회 33 (33): 92-104, 2022

      2 박진주 ; 최동주, "좌심실 수축 기능 저하 심부전증의 치료" 대한내과학회 88 (88): 127-134, 2015

      3 정윤경 ; 김수빈 ; 양정윤 ; 문상관 ; 정우상 ; 권승원 ; 조기호, "만성 경막하 혈종(Chronic subdural hematoma, CSDH)에 대한 오령산 증례보고 2례" 대한한방내과학회 38 (38): 259-263, 2017

      4 "元⋅鄧珍本金匱要略2-4b~2-5a" 燎原書店 86-87, 1988

      5 Nishida S, "Vascular Pharmacology of Mokuboito(Mu-Fang-Yi-Tang)and Its Constituents on the Smooth Muscle and the Endothelium in Rat Aorta" 4 (4): 335-341, 2007

      6 Bredy C, "New York Heart Association(NYHA)classification in adults with congenital heart disease : relation to objective measures of exercise and outcome" 4 (4): 51-58, 2018

      7 Arumugam S, "Japanese Kampo medicines for the treatment of common diseases" Academic Press 182-, 2017

      8 Pollock A, "Interventions for visual field defects in patients with stroke" 43 (43): e37-e38, 2012

      9 Ezaki H, "Effects of Mokuboito, a Japanese Kampo medicine, on symptoms in patients hospitalized for acute decompensated heart failure-A prospective randomized pilot study" 74 (74): 412-417, 2019

      10 Cho HJ, "Effects of Mokbanggi-tang on cardiac diuresis and heart rate" 5 (5): 28-34, 1984

      1 조은정, "코로나바이러스 감염증-19 백신 이상반응" 대한이비인후과학회 부산,울산,경남 지부회 33 (33): 92-104, 2022

      2 박진주 ; 최동주, "좌심실 수축 기능 저하 심부전증의 치료" 대한내과학회 88 (88): 127-134, 2015

      3 정윤경 ; 김수빈 ; 양정윤 ; 문상관 ; 정우상 ; 권승원 ; 조기호, "만성 경막하 혈종(Chronic subdural hematoma, CSDH)에 대한 오령산 증례보고 2례" 대한한방내과학회 38 (38): 259-263, 2017

      4 "元⋅鄧珍本金匱要略2-4b~2-5a" 燎原書店 86-87, 1988

      5 Nishida S, "Vascular Pharmacology of Mokuboito(Mu-Fang-Yi-Tang)and Its Constituents on the Smooth Muscle and the Endothelium in Rat Aorta" 4 (4): 335-341, 2007

      6 Bredy C, "New York Heart Association(NYHA)classification in adults with congenital heart disease : relation to objective measures of exercise and outcome" 4 (4): 51-58, 2018

      7 Arumugam S, "Japanese Kampo medicines for the treatment of common diseases" Academic Press 182-, 2017

      8 Pollock A, "Interventions for visual field defects in patients with stroke" 43 (43): e37-e38, 2012

      9 Ezaki H, "Effects of Mokuboito, a Japanese Kampo medicine, on symptoms in patients hospitalized for acute decompensated heart failure-A prospective randomized pilot study" 74 (74): 412-417, 2019

      10 Cho HJ, "Effects of Mokbanggi-tang on cardiac diuresis and heart rate" 5 (5): 28-34, 1984

      11 Lizhi Z, "Effect and safety of press-needle on chronic heart failure" 37 (37): 789-793, 2017

      12 Lee IG, "Differential Diagnosis and Treatment of Generalized Edema" 24 (24): 6-10, 2003

      13 Rosano G, "COVID-19vaccination in patients with heart failure : a position paper of the Heart Failure Association of the European Society of Cardiology" 23 (23): 1806-1818, 2021

      14 류경제 ; 김동현, "COVID-19 백신 접종 후 발생한 독성전방증후군 양상의 양안 안구염증 이상 반응 1예" 대한안과학회 63 (63): 625-629, 2022

      15 Ye X, "Association between BNT162b2or CoronaVac COVID-19 vaccines and major adverse cardiovascular events among individuals with cardiovascular disease" 118 (118): 2329-2338, 2022

      16 Ye X, "Association between BNT162b2or CoronaVac COVID-19 vaccines and major adverse cardiovascular events among individuals with cardiovascular disease" 118 (118): 2329-2338, 2022

      17 Ely JW, "Approach to leg edema of unclear etiology" 19 (19): 148-160, 2006

      18 권승원 ; Chul Jin ; 조기호, "An herbal medicine prescription (Oreongsan) developed as a new alternative treatment in patients with chronic subdural hematoma: a narrative review" 한국한의학연구원 8 (8): 26-30, 2019

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