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      광용적맥파 비맥동성분에 의한 혈관경직도 변화 분석 = Analysis of Arterial Stiffness Variation by Photoplethysmographic DC Component

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      https://www.riss.kr/link?id=A101119699

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      다국어 초록 (Multilingual Abstract)

      Assuming that photons absorbed by a vessel do not have acute variations, DC component reflect the basal blood volume (or diameter) before blood pulsation. Vascular stiffness and reflection is influenced by changes in basal blood volume (or diameter). This paper describes analysis of the characteristic variations of vascular stiffness, according to relative variations in DC components of the PPG signal (25-75%). For quantitative analysis, we have used parameters that were proposed previously, reflection and stiffness index, and the second derivative of PPG waveform, b/a and d/a. Significantly, the vascular stiffness and reflections were increased according to increase in DC component of the PPG signal for more than about 3% of baseline values. The systolic blood pressure were increased from $113.1{\times}13.18$ to $116.2{\times}13.319$ mmHg, about 2.76% (r = 0.991, P < 0.001) and the AC component of the PPG signal were decreased from $2.073{\times}2.287$ to $1.973{\times}2.2038$ arbitrary unit, about 5.09% (r = -0.993, P < 0.001). It is separated by DC median and correlation analysis was performed for analyzing vascular characteristics according to instantaneous DC variations. There are significant differences between two correlation coefficients in separated data.
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      Assuming that photons absorbed by a vessel do not have acute variations, DC component reflect the basal blood volume (or diameter) before blood pulsation. Vascular stiffness and reflection is influenced by changes in basal blood volume (or diameter). ...

      Assuming that photons absorbed by a vessel do not have acute variations, DC component reflect the basal blood volume (or diameter) before blood pulsation. Vascular stiffness and reflection is influenced by changes in basal blood volume (or diameter). This paper describes analysis of the characteristic variations of vascular stiffness, according to relative variations in DC components of the PPG signal (25-75%). For quantitative analysis, we have used parameters that were proposed previously, reflection and stiffness index, and the second derivative of PPG waveform, b/a and d/a. Significantly, the vascular stiffness and reflections were increased according to increase in DC component of the PPG signal for more than about 3% of baseline values. The systolic blood pressure were increased from $113.1{\times}13.18$ to $116.2{\times}13.319$ mmHg, about 2.76% (r = 0.991, P < 0.001) and the AC component of the PPG signal were decreased from $2.073{\times}2.287$ to $1.973{\times}2.2038$ arbitrary unit, about 5.09% (r = -0.993, P < 0.001). It is separated by DC median and correlation analysis was performed for analyzing vascular characteristics according to instantaneous DC variations. There are significant differences between two correlation coefficients in separated data.

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      참고문헌 (Reference)

      1 변미경, "지첨-족지 지수에 의한 동맥 혈관 특성화 연구" 대한의용생체공학회 28 (28): 777-785, 2007

      2 전석환, "자세변화에 따른 PWV 변화량의 평가" 대한의용생체공학회 30 (30): 129-134, 2009

      3 송상하, "맥파전달속도를 이용한 내중막 두께 추정에 관한 연구" 대한의용생공학회 30 (30): 401-411, 2009

      4 S. C. Millasseau, "The vascular impact of aging and vasoactive drugs: comparison of two digital volume pulse measurements" 16 : 467-472, 2003

      5 D. H. Bergel, "The static elastic properties of the arterial wall" 156 : 445-457, 1961

      6 X. Chanudet, "The influence of anthropometric factors, hemorheologic parameters and the level of arterial pressure on pulse wave velocity" 14 : 15-18, 1989

      7 J. van den Akker, "Small artery remodeling: current concepts and questions" 47 : 183-202, 2010

      8 T. H. Westhoff, "Small artery elasticity assessed by pulse wave analysis is no measure of endothelial dysfunction" 25 : 571-576, 2007

      9 J. Weinmann, "Reflection photoplethysmography of arterial-blood-volume pulses" 15 : 22-31, 1977

      10 R. Rauh, "Quantification of inspiratory-induced vasoconstrictive episodes: a comparison of laser Doppler fluxmetry and photoplethysmography" 23 : 344-348, 2003

      1 변미경, "지첨-족지 지수에 의한 동맥 혈관 특성화 연구" 대한의용생체공학회 28 (28): 777-785, 2007

      2 전석환, "자세변화에 따른 PWV 변화량의 평가" 대한의용생체공학회 30 (30): 129-134, 2009

      3 송상하, "맥파전달속도를 이용한 내중막 두께 추정에 관한 연구" 대한의용생공학회 30 (30): 401-411, 2009

      4 S. C. Millasseau, "The vascular impact of aging and vasoactive drugs: comparison of two digital volume pulse measurements" 16 : 467-472, 2003

      5 D. H. Bergel, "The static elastic properties of the arterial wall" 156 : 445-457, 1961

      6 X. Chanudet, "The influence of anthropometric factors, hemorheologic parameters and the level of arterial pressure on pulse wave velocity" 14 : 15-18, 1989

      7 J. van den Akker, "Small artery remodeling: current concepts and questions" 47 : 183-202, 2010

      8 T. H. Westhoff, "Small artery elasticity assessed by pulse wave analysis is no measure of endothelial dysfunction" 25 : 571-576, 2007

      9 J. Weinmann, "Reflection photoplethysmography of arterial-blood-volume pulses" 15 : 22-31, 1977

      10 R. Rauh, "Quantification of inspiratory-induced vasoconstrictive episodes: a comparison of laser Doppler fluxmetry and photoplethysmography" 23 : 344-348, 2003

      11 J. Hashimoto, "Pulse wave velocity and the second derivative of the finger photoplethysmogram in treated hypertensive patients: their relationship and associating factors" 20 : 2415-2422, 2002

      12 M.E.Safar, "Pulse pressure in essential hypertension: clinical and therapeutical implications" 7 : 769-776, 1989

      13 J.Allen, "Photoplethysmography and its application in clinical physiological measurement" 28 : 1-39, 2007

      14 P. J. Chowienczyk, "Photoplethysmographic assessment of pulse wave reflection: blunted response to endothelium- dependent beta2-adrenergic vasodilation in type II diabetes mellitus" 34 : 1999

      15 T. Lnne, "Noninvasive measurement of diameter changes in the distal abdominal aorta in man" 18 : 451-457, 1992

      16 D. Chemla, "Noninvasive assessment of arterial pressure" 14 : 317-321, 2008

      17 J. Allen, "Microvascular blood flow and skin temperature changes in the fingers following a deep nspiratory gasp" 23 : 365-373, 2002

      18 B. M. Pannier, "Methods and devices for measuring arterial compliance in humans" 15 : 743-753, 2002

      19 G. M. London, "Mechanism(s) of selective systolic blood pressure reduction after a low-dose combination of perindopril/indapamide in hypertensive subjects: comparison with atenolol" 43 : 92-99, 2004

      20 W. W. Nichols, "McDonald's blood flow in arteries : theoretic, experimental, and clinical principles, 5th ed" Oxford University Press 2005

      21 R. G. Asmar, "Improvement in blood pressure, arterial stiffness and wave reflections with a very-low-dose perindopril/ indapamide combination in hypertensive patient: a comparison with atenolol" 38 : 922-926, 2001

      22 H. Shin, "Ideal Filtering Approach on DCT Domain for Biomedical Signals: Index Blocked DCT Filtering Method (IB-DCTFM)" 34 (34): 741-753, 2010

      23 E. Zahedi, "Finger photoplethysmogram pulse amplitude changes induced by flow-mediated dilation" 29 : 625-637, 2008

      24 C. H. Chen, "Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure. Validation of generalized transfer function" 95 : 1827-1836, 1997

      25 M. J. Kool, "Diurnal pattern of vessel-wall properties of large arteries in healthy men" 9 : 108-109, 1991

      26 S. C. Millasseau, "Determination of age-related increases in large artery stiffness by digital pulse contour analysis" 103 : 371-377, 2002

      27 J. Webster, "Design of pulse oximeters" Taylor & Francis 1997

      28 e.J.G.Webster, "Design of Pulse Oximeters (Medical Science Series)" 19 : 1998

      29 S. C. Millasseau, "Contour analysis of the photoplethysmographic pulse measured at the finger" 24 : 1449-1456, 2006

      30 C. Z. Wang, "Comparison between reflection- mode photoplethysmography and arterial diameter change detected by ultrasound at the region of radial artery" 15 : 213-219, 2010

      31 A. A. Stadler, "Blood viscosity and optimal hematocrit in narrow tubes" 27 : 779-788, 1990

      32 K. Takazawa, "Assessment of vasoactive agents and vascular aging by the second derivative of photoplethysmogram waveform" 32 : 365-370, 1998

      33 L. A. Bortolotto, "Assessment of vascular aging and atherosclerosis in hypertensive subjects: second derivative of photoplethysmogram versus pulse wave velocity" 13 : 165-171, 2000

      34 R. L. Armentano, "Assessment of elastin and collagen contribution to aortic elasticity in conscious dogs" 260 : 1870-1877, 1991

      35 D. G. Brillante, "Arterial stiffness indices in healthy volunteers using non-invasive digital photoplethysmography" 17 : 116-123, 2008

      36 W. W. Nichols, "Arterial elastance and wave reflection augmentation of systolic blood pressure: deleterious effects and implications for therapy" 6 : 5-21, 2001

      37 H. Shin, "Adaptive threshold method for the peak detection of photoplethysmographic waveform" 2009

      38 J. Hagblad, "A technique based on laser Doppler flowmetry and photoplethysmography for simultaneously monitoring blood flow at different tissue depths" 48 : 415-422, 2010

      39 J. Pan, "A real-time QRS detection algorithm" 230-236, 1985

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