Antioxidant and antibacterial activities of Trema orientalis Linn : an indigenous medicinal plant of indian subcontinent

다국어 초록 (Multilingual Abstract)

Methanol and aqueous extract of leaves of Trema orientalis Linn. were subjected to the potential
antioxidant and antibacterial activities. The pharmacological interest of this plant coupled with
traditional use (antidiarrhoeal, antiseptic, analgesic etc) prompted to test for antioxidant and
antibacterial activities. The antioxidant potential of the methanolic extract was determined on the
basis of their scavenging activity of the stable 1,1-diphenyl-2-picryl hydrazyl free radical. IC50 of
the methanol extract of T. orientalis was 110.25 μg/ml which indicated the strong antioxidant
activity of the plant. However the aqueous extract showed mild antioxidant activity. In case of
antibacterial activities test, the extract was subjected for its effectiveness against both Grampositive
and Gram-negative bacteria in agar diffusion method. The zones of inhibition produced
by the crude methanol and aqueous extract against few sensitive strains were measured and
compared with those of standard antibiotic Gentamycin. It is evident that both extracts are active
against the bacteria at low concentrations. The obtained results provide a support for the use of
this plant in traditional medicine and suggest its further advance investigation.

다국어 초록 (Multilingual Abstract)

Methanol and aqueous extract of leaves of Trema orientalis Linn. were subjected to the potential
antioxidant and antibacterial activities. The pharmacological interest of this plant coupled with
traditional use (antidiarrhoeal, antiseptic, analgesic etc) prompted to test for antioxidant and
antibacterial activities. The antioxidant potential of the methanolic extract was determined on the
basis of their scavenging activity of the stable 1,1-diphenyl-2-picryl hydrazyl free radical. IC50 of
the methanol extract of T. orientalis was 110.25 μg/ml which indicated the strong antioxidant
activity of the plant. However the aqueous extract showed mild antioxidant activity. In case of
antibacterial activities test, the extract was subjected for its effectiveness against both Grampositive
and Gram-negative bacteria in agar diffusion method. The zones of inhibition produced
by the crude methanol and aqueous extract against few sensitive strains were measured and
compared with those of standard antibiotic Gentamycin. It is evident that both extracts are active
against the bacteria at low concentrations. The obtained results provide a support for the use of
this plant in traditional medicine and suggest its further advance investigation.

참고문헌 (Reference)

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