전립선비대증 환자에서 심박동수 변이 (Heart Rate Variability) 의 분석 = Analysis of Heart Rate Variability in Patients BPH

다국어 초록 (Multilingual Abstract)

Purpose: To characterize autonomic dysfunction in patients with benign prostatic hyperplasia (BPH), we
measured heart rate variability (HRV) and analyzed them compared with those of normal population.
Materials and Methods: ECG signals were obtained from 11 male patients (mean age, 63.1 years) and 23
healthy male controls (mean age, 57.0 years) in resting state. We analyzed their parameters of HRV and compared
them between groups.
Results: Time domain analysis including standard deviation of NN interval (SDNN), square root of mean of
sum of squares of differences between adjacent NN intervals (RMSSD) in patients with BPH were not significantly
different with those of controls. There were suggested evidence of decreased total power (TP), high frequency
(HF) in patients with BPH (p＜0.05) while no significant difference in other frequency domain such as very low
frequency (VLF), low frequency (LF) and LF/HF ratio.
Conclusion: This preliminary study shows that patients with BPH have different results on HRV study comparing
to controls. With the exception of LF and LF/HF ratio, all parameters of HRV in patients with BPH lower than
normal controls. TP, HF in patients with BPH significantly lower than that of normal controls. The decreased
values of HRV study means that they may have some kinds of disease or imbalance in autonomic nervous
system (ANS). So we suggest that HRV study may be a tool to describe the possibility of altered ANS activity
in patients with BPH. (J. Korean Continence Society 2005;9:17-22

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