The authors examined the immune function of 18 college entrance-exam repeater group (experimental group) who are considered to experience psychological stress, comparing with university student group(control group) who are not subjected to such condit...
The authors examined the immune function of 18 college entrance-exam repeater group (experimental group) who are considered to experience psychological stress, comparing with university student group(control group) who are not subjected to such condition. We measured the numbers and ratio of T-cell subsets( including T4 and T8) as well as B-cell and total lymphocyte count in both groups.
In comparing the experimental group with the control group, the former showed increased numbers of leukocyte, total lymphocyte, T-lymphocyte and B-lymphocyte. but significant difference was not found in the percentage of B-lymphocyte. T8 percentage, and T4/T8 ratio. But there was decrease in the percentage of T-lymphocyte and T4 in the experimental group.
As was shown in the results of the study, we confirmed partially the change of immune function, especially decrease of cell-mediated immunity, which may be the results of psychological stress associated with examination.
In our opinion, further studies should focus on the elucidation of whether these findings observed in our research are a direct effect of psychological stress or other attributable variables are involved. Moreover, the clinical implications of change of immune function in this study should be clarified in the subsequent study.
For this purpose, qualitative immunologic tests as well as neurondocrinologic tests should be included in the future studies.