한국산 약용식물 추출물의 알도즈 환원 효소 억제 효능 검색 (VI) = Screening of Korean Herbal Medicines with Inhibitory Effect on Aldose Reductase (VI)

다국어 초록 (Multilingual Abstract)

Aldose reductase (AR) has been implicated in the development of the diabetic complications. To discover novel treatments for diabetic complications from natural sources, 65 Korean herbal medicines have been investigated for inhibitory activities on AR. Of these, 23 herbal medicines exhibited a significant inhibitory activity compared with 3,3-tetramethyleneglutaric acid (TMG). Particularly, 8 herbal medicines, Acer tataricum (twig, stem and leaf), Acer tataricum (fruit), Rhododendron schlippenbachii (twig, stem and leaf), Weigela subsessilis (twig, stem and leaf), Acer mono (branch and leaf), Ailanthus altissima (twig, stem and leaf), Lindera obtusiloba (branch and leaf), Solidago serotina (whole plant) showed three times more potent inhibitory activity than the positive control, TMG.

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