복강경 결직장 수술 전 장준비: 경구 기계적 장세척군과 단순관장군의 전향적 비교연구 = The Impact of Bowel Preparation on Anastomotic Complications after Laparoscopic Colorectal Resection: A Prospective Comparative Study between Oral Polyethylene Glycol and Phosphate Enema

다국어 초록 (Multilingual Abstract)

Purpose: Although most randomized trials demonstrated no advantage of mechanical bowel preparation for colorectal
resection, an oral solution is still widely used. The aims of this study were to evaluate whether a single phosphate enema is
as effective as oral polyethylene glycol (PEG) solution in preventing anastomotic complications after laparoscopic colorectal
surgery and to examine the clinical courses of anastomotic complications.
Methods: Between September 2006 and December 2007, 309 patients underwent laparoscopic colorectal resection with
primary anastomosis. The bowel preparation used was PEG solution during initial period (PEG group), but since February
2007, a single phosphate enema (enema group) was utilized. Postoperative data were prospectively recorded. In patients
with anastomotic complications, the clinical course was compared between the two groups.
Results: There were 150 patients in the PEG group and 159 patients in the enema group. Demographics did not differ between
the two groups. Anastomotic leakage occurred in 3.3 percent of the patients in the PEG group and 5.7 percent of the
patients in the enema group (P=0.326). The rates of anastomotic bleeding were 2.0 and 2.5 percent, respectively (P=0.761).
The hospital stays for patients with anastomotic complication were not different between the two groups (P=0.137), but
patients in the PEG group (80%) needed reoperation more frequently than those in the enema group (11.1%) (P=0.023).
Conclusion: These results suggest that laparoscopic colorectal surgery may be safely performed with a single phosphate
enema instead of oral polyethylene glycol.

다국어 초록 (Multilingual Abstract)

Purpose: Although most randomized trials demonstrated no advantage of mechanical bowel preparation for colorectal
resection, an oral solution is still widely used. The aims of this study were to evaluate whether a single phosphate enema is
as effective as oral polyethylene glycol (PEG) solution in preventing anastomotic complications after laparoscopic colorectal
surgery and to examine the clinical courses of anastomotic complications.
Methods: Between September 2006 and December 2007, 309 patients underwent laparoscopic colorectal resection with
primary anastomosis. The bowel preparation used was PEG solution during initial period (PEG group), but since February
2007, a single phosphate enema (enema group) was utilized. Postoperative data were prospectively recorded. In patients
with anastomotic complications, the clinical course was compared between the two groups.
Results: There were 150 patients in the PEG group and 159 patients in the enema group. Demographics did not differ between
the two groups. Anastomotic leakage occurred in 3.3 percent of the patients in the PEG group and 5.7 percent of the
patients in the enema group (P=0.326). The rates of anastomotic bleeding were 2.0 and 2.5 percent, respectively (P=0.761).
The hospital stays for patients with anastomotic complication were not different between the two groups (P=0.137), but
patients in the PEG group (80%) needed reoperation more frequently than those in the enema group (11.1%) (P=0.023).
Conclusion: These results suggest that laparoscopic colorectal surgery may be safely performed with a single phosphate
enema instead of oral polyethylene glycol.

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