당뇨병 유,무에 따른 척수장애인의 복부지방, 아디포사이토카인 및 대사증후군 위험인자의 비교 = Comparison of Abdominal Fat, Adipocytokine, Metabolic Syndrome Risk Factors between Diabetes Group and None-diabetes Group in Individuals with Spinal Cord Injury

국문 초록 (Abstract)

본 연구는 성인 남성 척수장애인을 대상으로 제2형 당뇨병 유·무에 따른 복부지방, 아디포사이토카인 및 대사증후군 위험인자의 차이를 규명하기 위하여 제2형 당뇨집단 10명, 비당뇨집단 10명으로 구성하여 체중, 복부지방, 체력, 아디포사이토카인, 그리고 대사증후군 위험인자를 비교·분석하였다. 두 집단의 측정값을 비교·분석하기 위해 독립 t-검증을 실시하였다. 그 결과 당뇨 유·무에 따른 척수장애인의 체중의 차이는 유의하지 않았으나, TFA와 VFA는 당뇨집단이 유의하게 높게 나타났으며, SFA와 VSR는 비당뇨집단보다 당뇨집단이 높게 나타났다. 또한 당뇨 유·무에 따른 척수장애인의 우악력, 좌악력, VO2peak, HRpeak, 그리고 HRrest는 유의한 차이는 없었다. 그리고 당뇨 유·무에 따른 척수장애인의 렙틴과 TNF-α는 유의한 차이는 없었으며, 아디포넥틴은 당뇨집단이 비당뇨집단보다 유의하게 높았다. 또한 대사증후군 위험인자 중 TG, HDL, TG, SBP 및 DBP의 유의한 차이는 없었으나, LDL-C, 공복 혈당, 공복 인슐린, 그리고 HOMA(IR)은 당뇨집단이 비당뇨집단보다 유의하게 높게 나타났다. 이러한 결과들을 통해 당뇨병 유·무와 상관없이 두 집단 모두 복부비만의 심각성과 함께 당뇨병이 있는 척수장애인의 고지혈증과 인슐린 저항성의 문제점이 나타났다. 따라서 향후 연구에서는 이러한 척수장애인들의 복부지방의 감소와 혈당 및 지질 감소를 위한 다양한 운동프로그램이 개발 및 적용이 요구된다.

다국어 초록 (Multilingual Abstract)

Ⅰwas to examine the difference of male diabetic spinal cord individuals` weight, abdominal fat, physical strength, adipocytokine, according to the having typeⅡ diabetes, and metabolic syndrome risk factors. The value of measurement of this research was compared and analyzed from male diabetic spinal cord individuals` two group 20 persons: typeⅡ diabetes group 10 persons and none diabetes group 10persons. I was operated independent t prove in order to compare the value of measurement between the two group. The followings are the summery from this research. 1) The difference of weight of spinal cord injuries, according to the diabetes existence, was not apparent, but the diabetes group`s TFA and VFA were high clearly, and diabetes group`s SFA and VSR were higher than none diabetes group. 2) There was no difference of right and left grasping power, VO2peak, HRpeak, and HRrest in individuals with spinal cord injuries, according to the diabetes existence. 3) There was no apparent difference of leptin and TNF-α in individuals with spinal cord injuries, according to the diabetes existence, but diabets group`s adiponetin was higher than none diabetes group. 4) There was no apparent difference of TG, HDL, TG, SBP and DBP of spinal cord injured individuals, according to the diabetes existence, but the diabetes group`s LDL-C, an empty stomach blood sugar and insulin, and HOMA(IR) were higher than none diabetes group. From these conclusions, TFA, VFA, LDL-C, an empty blood and insulin, HOMA(IR), low adiponetin of male diabetic spinal cord injured person, having typeⅡ diabetes, were higher than none diabetes group.

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