베타용혈성 연쇄구균의 R plasmid에 관한 연구 = A Study on R Plasmid of β-hemolytic Streptococci

다국어 초록 (Multilingual Abstract)

Since plasmid showing antibiotic resistance in β-hemolytic streptococci had been discovered later than other bacteria, few cases of R plasmid have been reported until now. The resistant rate of this organism was increased recently. To evaluate the pattern of antibiotic susceptibility and the mechanism of resistance, minimal inhibitory concentrations (MIC) were determined by agar dilution method and presence of R plasmid was examined by modified LeBlance-Lee method in total 70 strains of β-hemolytic streptococci isolated from clinical specimens at the Department of Clinical Pathology, Seoul National University Hospital between September 1987 and January, 1988.
In case of group A β-hemolytic streptococci, all strains were susceptible to penicillin, but 3 of 26 strains showed resistant to erythromycin. 12 strains of 16 group B β-hemolytic streptococci, were resistant to tetracycline. Arnong 6 group C β-hemolytic streptococci, 3 and 2 strains showed resistant to penicillin and erythromycin, respectively. All of group G. and non-A, B, C, G β-hemolytic streptococci were susceptible to penicillin.