PDMS 블레이드 코팅법을 이용한 종이-기반 바이오센서칩 제작 = Fabrication of Paper-based Biosensor Chip Using Polydimethylsiloxane Blade Coating Method

다국어 초록 (Multilingual Abstract)

This paper proposes the polydimethylsiloxane (PDMS) blade coating method for fabrication of paperbased analytical device (PAD) that is able to monitor the disease diagnosis and progress without special analytical equipment. The mold that has PAD design is easily modified by using laser cutting technique. And the fabricated mold is used for hydrophobic barrier formation by blade coating. We have optimized the stable formation of PDMS hydrophobic barrier as blade coating condition, which is established by analyzing the structure of the PDMS hydrophobic barrier and change of hydrophilic channel size as thickness of the ink and contact time with the chromatography paper. Based on optimal condition, we demonstrate that PAD as biosensor can apply to detect protein, glucose, and metal ion without special analysis equipment.

참고문헌 (Reference)

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