남생이(Geoclemys reevesii) 소뇌에 있어서 raf Protein Kinase의 면역세포화학적 분포 = The Immunocytochemical Distribution of raf Protein Kinase in the Cerebellum of Geoclemys reevesii

다국어 초록 (Multilingual Abstract)

Raf oncogene is a transforming gene of retrovirus. 3611-murine sarcoma virus(3611-MSV) and there are active genes known in man. a-raf, b0raf and c-raf, A-raf and c-raf encode cytoplasmic protein related with serine/threonine specific protein kinase activity and also they are similar to protein kinase C in the functional structure and cellular distribution.
In this study. the distribution of a-raf and coraf protein kinase was researched in the cerebellum of Geoclemys reevesii. Generally raf protein kinase was distributed limitedly in Purkinje cell layer. granular cell layer. and molecular cell layer of cerebellum. Especially it was strongly immunoreactive in the Purkinje cell. In Geoclemys reevesii, it was notable that the immunolabeling of a-raf protein kinase was shown a higher intensity than that of c-raf protein kinase.