Sedentary behavior (SB) and physical inactivity (PI) are among the principal changeable risk factors worldwide for cardiovascular disease (CVD) and all-cause mortality. The increment in physical activity (PA) and aerobic exercise (AE) leading to enhan...
Sedentary behavior (SB) and physical inactivity (PI) are among the principal changeable risk factors worldwide for cardiovascular disease (CVD) and all-cause mortality. The increment in physical activity (PA) and aerobic exercise (AE) leading to enhanced levels of cardiorespiratory fitness (CF) is required to prevent and manage CVD, particularly coronary artery disease and heart failure. Despite robust evidence supporting the benefits of PA and AE for the prevention and management of CVD, PI is vastly widespread worldwide. This study reviews the negative influence of SB and PI, as well as the positive effects of PA, AE and CF for the prevention and management of CVD. It also discusses the mechanisms by which PA and AE can promote cardiovascular health and decrease the burden of CVD.
Considerable efforts at decreasing SB and PI while increasing PA, AE, and CF are required.